About the Authors

Ann W. Walsh

Affiliation Research and Development, Bristol-Myers Squibb Inc., Wallingford, Connecticut, United States of America

David R. Langley

david.langley@bms.com (DRL); daniel.tenney@bms.com (DJT)

Affiliation Research and Development, Bristol-Myers Squibb Inc., Wallingford, Connecticut, United States of America

Richard J. Colonno

Current address: Presidio Pharmaceuticals, San Francisco, California, United States of America

Affiliation Research and Development, Bristol-Myers Squibb Inc., Wallingford, Connecticut, United States of America

Daniel J. Tenney

david.langley@bms.com (DRL); daniel.tenney@bms.com (DJT)

Affiliation Research and Development, Bristol-Myers Squibb Inc., Wallingford, Connecticut, United States of America

Competing Interests

All authors were paid employees of Bristol-Myers Squibb at the time of the work and all hold stock or stock options in the company. Entecavir, the subject of the paper, is a marketed product of Bristol-Myers Squibb. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials in the paper, as detailed in the guide to authors.

Author Contributions

Conceived and designed the experiments: AWW DRL RJC DJT. Performed the experiments: AWW DRL. Analyzed the data: AWW DRL RJC DJT. Wrote the paper: AWW DRL RJC DJT.