About the Authors

Laura Musazzi

Contributed equally to this work with: Laura Musazzi, Marco Milanese

Affiliation Department of Pharmacological Sciences, Center of Neuropharmacology and Center of Excellence on Neurodegenerative Diseases, University of Milano, Milano, Italy

Marco Milanese

Contributed equally to this work with: Laura Musazzi, Marco Milanese

Affiliations Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genova, Genova, Italy, Center of Excellence for Biomedical Research and National Institute of Neuroscience, Genova, Italy

Pasqualina Farisello

Affiliations Department of Neuroscience and Brain Technologies, The Italian Institute of Technology, Genova, Italy, Department of Experimental Medicine, Section of Physiology, University of Genova and National Institute of Neuroscience, Genova, Italy

Simona Zappettini

Affiliations Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genova, Genova, Italy, Center of Excellence for Biomedical Research and National Institute of Neuroscience, Genova, Italy

Daniela Tardito

Affiliation Department of Pharmacological Sciences, Center of Neuropharmacology and Center of Excellence on Neurodegenerative Diseases, University of Milano, Milano, Italy

Valentina S. Barbiero

Affiliation Department of Pharmacological Sciences, Center of Neuropharmacology and Center of Excellence on Neurodegenerative Diseases, University of Milano, Milano, Italy

Tiziana Bonifacino

Affiliations Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genova, Genova, Italy, Center of Excellence for Biomedical Research and National Institute of Neuroscience, Genova, Italy

Alessandra Mallei

Affiliation Department of Pharmacological Sciences, Center of Neuropharmacology and Center of Excellence on Neurodegenerative Diseases, University of Milano, Milano, Italy

Pietro Baldelli

Affiliations Department of Neuroscience and Brain Technologies, The Italian Institute of Technology, Genova, Italy, Department of Experimental Medicine, Section of Physiology, University of Genova and National Institute of Neuroscience, Genova, Italy

Giorgio Racagni

Affiliations Department of Pharmacological Sciences, Center of Neuropharmacology and Center of Excellence on Neurodegenerative Diseases, University of Milano, Milano, Italy, Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genova, Genova, Italy, Department of Neuroscience and Brain Technologies, The Italian Institute of Technology, Genova, Italy, Istituto di Ricovero e Cura a Carattere Scientifico San Giovanni di Dio - Fatebenefratelli, Brescia, Italy, Center of Excellence for Biomedical Research and National Institute of Neuroscience, Genova, Italy, Department of Experimental Medicine, Section of Physiology, University of Genova and National Institute of Neuroscience, Genova, Italy

Maurizio Raiteri

Affiliations Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genova, Genova, Italy, Center of Excellence for Biomedical Research and National Institute of Neuroscience, Genova, Italy

Fabio Benfenati

Affiliations Department of Neuroscience and Brain Technologies, The Italian Institute of Technology, Genova, Italy, Department of Experimental Medicine, Section of Physiology, University of Genova and National Institute of Neuroscience, Genova, Italy

Giambattista Bonanno

These authors also contributed equally to this work.

Affiliations Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genova, Genova, Italy, Center of Excellence for Biomedical Research and National Institute of Neuroscience, Genova, Italy

Maurizio Popoli

maurizio.popoli@unimi.it

These authors also contributed equally to this work.

Affiliation Department of Pharmacological Sciences, Center of Neuropharmacology and Center of Excellence on Neurodegenerative Diseases, University of Milano, Milano, Italy

Competing Interests

MP and GR declare they are acting as consultants for Servier Pharmaceuticals (France). All other authors declare no conflict of interest. This does not alter our adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: PB GR MR FB GB MP. Performed the experiments: LM MM PF SZ VSB TB AM. Analyzed the data: LM MM PF SZ DT AM PB GB. Wrote the paper: LM FB GB MP.