Hepatitis C Lipo-Viro-Particle from Chronically Infected Patients Interferes with TLR4 Signaling in Dendritic Cell

Sophie Agaugué; Laure Perrin-Cocon; Patrice André; Vincent Lotteau

doi:10.1371/journal.pone.0000330

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Open Access

Peer-reviewed

Research Article

Hepatitis C Lipo-Viro-Particle from Chronically Infected Patients Interferes with TLR4 Signaling in Dendritic Cell

Sophie Agaugué ,

Contributed equally to this work with: Sophie Agaugué, Laure Perrin-Cocon

Current address: Department of Experimental Medicine (DIMES), Sezione Istologia, Genova, Italy

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U851, Lyon, France, Université de Lyon, Lyon-Gerland, France
⨯
Laure Perrin-Cocon ,

Contributed equally to this work with: Sophie Agaugué, Laure Perrin-Cocon

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U851, Lyon, France, Université de Lyon, Lyon-Gerland, France
⨯
Patrice André,

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U851, Lyon, France, Université de Lyon, Lyon-Gerland, France, Hospices Civils de Lyon, Hôpital de la Croix Rousse, Laboratoire de Virologie, France
⨯
Vincent Lotteau

*To whom correspondence should be addressed. E-mail: lotteau@cervi-lyon.inserm.fr

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U851, Lyon, France, Université de Lyon, Lyon-Gerland, France, Hospices Civils de Lyon, Hôpital de la Croix Rousse, Laboratoire de Virologie, France
⨯

Hepatitis C Lipo-Viro-Particle from Chronically Infected Patients Interferes with TLR4 Signaling in Dendritic Cell

Sophie Agaugué,
Laure Perrin-Cocon,
Patrice André,
Vincent Lotteau

Published: March 28, 2007
https://doi.org/10.1371/journal.pone.0000330

About the Authors

Sophie Agaugué

Contributed equally to this work with: Sophie Agaugué, Laure Perrin-Cocon

Current address: Department of Experimental Medicine (DIMES), Sezione Istologia, Genova, Italy

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U851, Lyon, France, Université de Lyon, Lyon-Gerland, France

Laure Perrin-Cocon

Contributed equally to this work with: Sophie Agaugué, Laure Perrin-Cocon

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U851, Lyon, France, Université de Lyon, Lyon-Gerland, France

Patrice André

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM), U851, Lyon, France, Université de Lyon, Lyon-Gerland, France, Hospices Civils de Lyon, Hôpital de la Croix Rousse, Laboratoire de Virologie, France

Vincent Lotteau

*To whom correspondence should be addressed. E-mail: lotteau@cervi-lyon.inserm.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VL LP SA PA. Performed the experiments: LP SA PA. Analyzed the data: VL LP SA PA. Wrote the paper: VL LP SA PA.

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Secretion
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T cells
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Immune receptor signaling
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Lipoproteins
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Cytokines
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Cytokine therapy
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Lipids
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Toll-like receptors
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