A Research and Development Agenda for the Control and Elimination of Human Helminthiases

Jürg Utzinger

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001646

A Research Agenda for Helminth Diseases of Humans: Basic Research and Enabling Technologies to Support Control and Elimination of Helminthiases

Sara Lustigman, Peter Geldhof, Warwick N. Grant, Mike Y. Osei-Atweneboana, Banchob Sripa, María-Gloria Basáñez

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001445

A Research Agenda for Helminth Diseases of Humans: Towards Control and Elimination

Boakye A. Boatin, María-Gloria Basáñez, Roger K. Prichard, Kwablah Awadzi, Rashida M. Barakat, Héctor H. García, Andrea Gazzinelli, Warwick N. Grant, James S. McCarthy, Eliézer K. N'Goran, Mike Y. Osei-Atweneboana, Banchob Sripa, Guo-Jing Yang, Sara Lustigman

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001547

A Research Agenda for Helminth Diseases of Humans: Modelling for Control and Elimination

María-Gloria Basáñez, James S. McCarthy, Michael D. French, Guo-Jing Yang, Martin Walker, Manoj Gambhir, Roger K. Prichard, Thomas S. Churcher

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001548

A Research Agenda for Helminth Diseases of Humans: Intervention for Control and Elimination

Roger K. Prichard, María-Gloria Basáñez, Boakye A. Boatin, James S. McCarthy, Héctor H. García, Guo-Jing Yang, Banchob Sripa, Sara Lustigman

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001549

A Research Agenda for Helminth Diseases of Humans: The Problem of Helminthiases

Sara Lustigman, Roger K. Prichard, Andrea Gazzinelli, Warwick N. Grant, Boakye A. Boatin, James S. McCarthy, María-Gloria Basáñez

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001582

A Research Agenda for Helminth Diseases of Humans: Diagnostics for Control and Elimination Programmes

James S. McCarthy, Sara Lustigman, Guo-Jing Yang, Rashida M. Barakat, Héctor H. García, Banchob Sripa, Arve Lee Willingham, Roger K. Prichard, María-Gloria Basáñez

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001601

A Research Agenda for Helminth Diseases of Humans: Health Research and Capacity Building in Disease-Endemic Countries for Helminthiases Control

Mike Y. Osei-Atweneboana, Sara Lustigman, Roger K. Prichard, Boakye A. Boatin, María-Gloria Basáñez

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001602

A Research Agenda for Helminth Diseases of Humans: Social Ecology, Environmental Determinants, and Health Systems

Andrea Gazzinelli, Rodrigo Correa-Oliveira, Guo-Jing Yang, Boakye A. Boatin, Helmut Kloos

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001603

Community Risk Factors for Ocular Chlamydia Infection in Niger: Pre-Treatment Results from a Cluster-Randomized Trachoma Trial

Abdou Amza, Boubacar Kadri, Baido Nassirou, Nicole E. Stoller, Sun N. Yu, Zhaoxia Zhou, Stephanie Chin, Sheila K. West, Robin L. Bailey, David C. W. Mabey, Jeremy D. Keenan, Travis C. Porco, Thomas M. Lietman, Bruce D. Gaynor, for the PRET Partnership

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001586

Pathogen-Specific Epitopes as Epidemiological Tools for Defining the Magnitude of Mycobacterium leprae Transmission in Areas Endemic for Leprosy

Marcia V. S. B. Martins, Marjorie M. da S. Guimarães, John S. Spencer, Mariana A. V. B. Hacker, Luciana S. Costa, Fernanda M. Carvalho, Annemieke Geluk, Jolien J. van der Ploeg-van Schip, Maria A. A. Pontes, Heitor S. Gonçalves, Janvier P. de Morais, Tereza J. P. G. Bandeira, Maria C. V. Pessolani, Patrick J. Brennan, Geraldo M. B. Pereira

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001616

Innate Immune Response to Rift Valley Fever Virus in Goats

Charles K. Nfon, Peter Marszal, Shunzhen Zhang, Hana M. Weingartl

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001623

Selective Inhibitors of Protozoan Protein N-myristoyltransferases as Starting Points for Tropical Disease Medicinal Chemistry Programs

Andrew S. Bell, James E. Mills, Gareth P. Williams, James A. Brannigan, Anthony J. Wilkinson, Tanya Parkinson, Robin J. Leatherbarrow, Edward W. Tate, Anthony A. Holder, Deborah F. Smith

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001625

Regulatory T Cells in the Pathogenesis and Healing of Chronic Human Dermal Leishmaniasis Caused by Leishmania (Viannia) Species

Daniel Rodriguez-Pinto, Adriana Navas, Víctor Manuel Blanco, Lady Ramírez, Daniel Garcerant, Adriana Cruz, Noah Craft, Nancy Gore Saravia

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001627

Deficient Regulatory T Cell Activity and Low Frequency of IL-17-Producing T Cells Correlate with the Extent of Cardiomyopathy in Human Chagas' Disease

Paulo Marcos Matta Guedes, Fredy Roberto Salazar Gutierrez, Grace Kelly Silva, Renata Dellalibera-Joviliano, Gerson Jhonatan Rodrigues, Lusiane Maria Bendhack, Anis Rassi Jr, Anis Rassi, André Schmidt, Benedito Carlos Maciel, José Antonio Marin Neto, João Santana Silva

PLOS Neglected Tropical Diseases: published April 24, 2012 | https://doi.org/10.1371/journal.pntd.0001630

Additive Protection by Antioxidant and Apoptosis-Inhibiting Effects on Mosquito Cells with Dengue 2 Virus Infection

Tien-Huang Chen, Yin-Ping Lo, Chao-Fu Yang, Wei-June Chen

PLOS Neglected Tropical Diseases: published April 17, 2012 | https://doi.org/10.1371/journal.pntd.0001613

Dengue Deaths in Puerto Rico: Lessons Learned from the 2007 Epidemic

Kay M. Tomashek, Christopher J. Gregory, Aidsa Rivera Sánchez, Matthew A. Bartek, Enid J. Garcia Rivera, Elizabeth Hunsperger, Jorge L. Muñoz-Jordán, Wellington Sun

PLOS Neglected Tropical Diseases: published April 17, 2012 | https://doi.org/10.1371/journal.pntd.0001614

Long-Term Impact of the World Bank Loan Project for Schistosomiasis Control: A Comparison of the Spatial Distribution of Schistosomiasis Risk in China

Zhijie Zhang, Rong Zhu, Michael P. Ward, Wanghong Xu, Lijuan Zhang, Jiagang Guo, Fei Zhao, Qingwu Jiang

PLOS Neglected Tropical Diseases: published April 17, 2012 | https://doi.org/10.1371/journal.pntd.0001620

Synergistic Interactions between the NS3_hel and E Proteins Contribute to the Virulence of Dengue Virus Type 1

Luana de Borba, Daisy M. Strottmann, Lucia de Noronha, Peter W. Mason, Claudia N. Duarte dos Santos

PLOS Neglected Tropical Diseases: published April 17, 2012 | https://doi.org/10.1371/journal.pntd.0001624

Higher Expression of CCL2, CCL4, CCL5, CCL21, and CXCL8 Chemokines in the Skin Associated with Parasite Density in Canine Visceral Leishmaniasis

Daniel Menezes-Souza, Renata Guerra-Sá, Cláudia Martins Carneiro, Juliana Vitoriano-Souza, Rodolfo Cordeiro Giunchetti, Andréa Teixeira-Carvalho, Denise Silveira-Lemos, Guilherme Corrêa Oliveira, Rodrigo Corrêa-Oliveira, Alexandre Barbosa Reis

PLOS Neglected Tropical Diseases: published April 10, 2012 | https://doi.org/10.1371/journal.pntd.0001566

Multiple Mitochondrial Introgression Events and Heteroplasmy in Trypanosoma cruzi Revealed by Maxicircle MLST and Next Generation Sequencing

Louisa A. Messenger, Martin S. Llewellyn, Tapan Bhattacharyya, Oscar Franzén, Michael D. Lewis, Juan David Ramírez, Hernan J. Carrasco, Björn Andersson, Michael A. Miles

PLOS Neglected Tropical Diseases: published April 10, 2012 | https://doi.org/10.1371/journal.pntd.0001584

Prevalence of Trachoma in Unity State, South Sudan: Results from a Large-Scale Population-Based Survey and Potential Implications for Further Surveys

Tansy Edwards, Jennifer Smith, Hugh J. W. Sturrock, Lucia W. Kur, Anthony Sabasio, Timothy P. Finn, Mounir Lado, Danny Haddad, Jan H. Kolaczinski

PLOS Neglected Tropical Diseases: published April 10, 2012 | https://doi.org/10.1371/journal.pntd.0001585

Five-Year Longitudinal Assessment of the Downstream Impact on Schistosomiasis Transmission following Closure of the Three Gorges Dam

Darren J. Gray, Aaron P. Thrift, Gail M. Williams, Feng Zheng, Yue-Sheng Li, Jiagang Guo, Honggen Chen, Tianping Wang, Xin Jiang Xu, Rong Zhu, Hongqing Zhu, Chun Li Cao, Dan Dan Lin, Zhen Yuan Zhao, Robert S. Li, George M. Davis, Donald P. McManus

PLOS Neglected Tropical Diseases: published April 10, 2012 | https://doi.org/10.1371/journal.pntd.0001588

Related Articles

1. Correction: Five-Year Longitudinal Assessment of the Downstream Impact on Schistosomiasis Transmission following Closure of the Three Gorges Dam

Canine Skin and Conjunctival Swab Samples for the Detection and Quantification of Leishmania infantum DNA in an Endemic Urban Area in Brazil

Sidney de Almeida Ferreira, Rodrigo Souza Leite, Leonardo Trindade Ituassu, Gregório Guilherme Almeida, Daniel Menezes Souza, Ricardo Toshio Fujiwara, Antero Silva Ribeiro de Andrade, Maria Norma Melo

PLOS Neglected Tropical Diseases: published April 10, 2012 | https://doi.org/10.1371/journal.pntd.0001596

Epidemiology and Molecular Relationships of Cryptosporidium spp. in People, Primates, and Livestock from Western Uganda

Stephanie J. Salyer, Thomas R. Gillespie, Innocent B. Rwego, Colin A. Chapman, Tony L. Goldberg

PLOS Neglected Tropical Diseases: published April 10, 2012 | https://doi.org/10.1371/journal.pntd.0001597

In Vitro and In Vivo Efficacy of Ether Lipid Edelfosine against Leishmania spp. and SbV-Resistant Parasites

Rubén E. Varela-M, Janny A. Villa-Pulgarin, Edward Yepes, Ingrid Müller, Manuel Modolell, Diana L. Muñoz, Sara M. Robledo, Carlos E. Muskus, Julio López-Abán, Antonio Muro, Iván D. Vélez, Faustino Mollinedo

PLOS Neglected Tropical Diseases: published April 10, 2012 | https://doi.org/10.1371/journal.pntd.0001612

Prevalence, Features and Risk Factors for Malaria Co-Infections amongst Visceral Leishmaniasis Patients from Amudat Hospital, Uganda

Erika van den Bogaart, Marieke M. Z. Berkhout, Emily R. Adams, Pètra F. Mens, Elizabeth Sentongo, Dawson B. Mbulamberi, Masja Straetemans, Henk D. F. H. Schallig, Francois Chappuis

PLOS Neglected Tropical Diseases: published April 10, 2012 | https://doi.org/10.1371/journal.pntd.0001617

Human and Canine Echinococcosis Infection in Informal, Unlicensed Abattoirs in Lima, Peru

Maria M. Reyes, Claudia P. Taramona, Mardeli Saire-Mendoza, Cesar M. Gavidia, Eduardo Barron, Belgees Boufana, Philip S. Craig, Luis Tello, Hector H. Garcia, Saul J. Santivañez

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001462

Investigation of the Proteolytic Functions of an Expanded Cercarial Elastase Gene Family in Schistosoma mansoni

Jessica R. Ingram, Salma B. Rafi, A. Alegra Eroy-Reveles, Manisha Ray, Laura Lambeth, Ivy Hsieh, Debbie Ruelas, K. C. Lim, Judy Sakanari, Charles S. Craik, Matthew P. Jacobson, James H. McKerrow

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001589

Detection of Mycobacterium ulcerans by the Loop Mediated Isothermal Amplification Method

Anthony Ablordey, Diana Ackon Amissah, Isaac Frimpong Aboagye, Ben Hatano, Toshio Yamazaki, Tetsutaro Sata, Koichi Ishikawa, Harutaka Katano

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001590

Population Structure and Transmission Dynamics of Plasmodium vivax in the Republic of Korea Based on Microsatellite DNA Analysis

Moritoshi Iwagami, Megumi Fukumoto, Seung-Young Hwang, So-Hee Kim, Weon-Gyu Kho, Shigeyuki Kano

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001592

The Schistosoma mansoni Tegumental-Allergen-Like (TAL) Protein Family: Influence of Developmental Expression on Human IgE Responses

Colin M. Fitzsimmons, Frances M. Jones, Alex Stearn, Iain W. Chalmers, Karl F. Hoffmann, Jakub Wawrzyniak, Shona Wilson, Narcis B. Kabatereine, David W. Dunne

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001593

IFN-γ Plays a Unique Role in Protection against Low Virulent Trypanosoma cruzi Strain

Adele A. Rodrigues, Jasson S. S. Saosa, Grace K. da Silva, Flávia A. Martins, Aline A. da Silva, Cecílio P. da Silva Souza Neto, Catarina V. Horta, Dario S. Zamboni, João S. da Silva, Eloisa A. V. Ferro, Claudio V. da Silva

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001598

Genetic and Anatomic Determinants of Enzootic Venezuelan Equine Encephalitis Virus Infection of Culex (Melanoconion) taeniopus

Joan L. Kenney, A. Paige Adams, Rodion Gorchakov, Grace Leal, Scott C. Weaver

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001606

Second External Quality Assurance Study for the Serological Diagnosis of Hantaviruses in Europe

Camille Escadafal, Tatjana Avšič-Županc, Olli Vapalahti, Bo Niklasson, Anette Teichmann, Matthias Niedrig, Oliver Donoso-Mantke

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001607

Increased Birth Weight Associated with Regular Pre-Pregnancy Deworming and Weekly Iron-Folic Acid Supplementation for Vietnamese Women

Luca Passerini, Gerard J. Casey, Beverley A. Biggs, Dai T. Cong, Luong B. Phu, Tran Q. Phuc, Marco Carone, Antonio Montresor

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001608

Incrimination of Phlebotomus kandelakii and Phlebotomus balcanicus as Vectors of Leishmania infantum in Tbilisi, Georgia

Ekaterina Giorgobiani, Phillip G. Lawyer, Giorgi Babuadze, Nato Dolidze, Ryan C. Jochim, Lamzira Tskhvaradze, Konstantin Kikaleishvili, Shaden Kamhawi

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001609

KSAC, a Defined Leishmania Antigen, plus Adjuvant Protects against the Virulence of L. major Transmitted by Its Natural Vector Phlebotomus duboscqi

Regis Gomes, Clarissa Teixeira, Fabiano Oliveira, Phillip G. Lawyer, Dia-Eldin Elnaiem, Claudio Meneses, Yasuyuki Goto, Ajay Bhatia, Randall F. Howard, Steven G. Reed, Jesus G. Valenzuela, Shaden Kamhawi

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001610

Elevated Adaptive Immune Responses Are Associated with Latent Infections of Wuchereria bancrofti

Kathrin Arndts, Susanne Deininger, Sabine Specht, Ute Klarmann, Sabine Mand, Tomabu Adjobimey, Alexander Y. Debrah, Linda Batsa, Alexander Kwarteng, Christian Epp, Mark Taylor, Ohene Adjei, Laura E. Layland, Achim Hoerauf

PLOS Neglected Tropical Diseases: published April 3, 2012 | https://doi.org/10.1371/journal.pntd.0001611