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December 2011

The enterotoxigenic E. coli (ETEC) are a common cause of diarrheal illness in developing countries where these organisms cause hundreds of thousands of deaths annually. Antigenic variability among known ETEC vaccine targets has prompted searches for additional conserved antigens that could be used to prevent ETEC infections. In this issue, Harris et al. explore the use of a highly conserved class of surface proteins known as autotransporters as potential ETEC vaccine constituents. This composite image shows host cell membrane (green), cellular actin (red), and nucleic acid (bacteria and cellular nuclei, blue).

Image Credit: James M. Fleckenstein, Thomas Wong, Michael Whitt (University of Tennessee Health Sciences Center)

Editorial

An Interfaith Dialogue on the Neglected Tropical Diseases

Peter J. Hotez, Serap Aksoy

Photo Quiz

Generalized Serpiginous Eruption during Immunosuppressive Treatment for Leprosy Reactive Neuritis

Carlos Gustavo Wambier, Fernanda Britta Maitto Lemos, Mark Aaron Cappel, Fernando Bellissimo-Rodrigues, Norma Tiraboschi Foss

Reviews

The Emerging Story of Disability Associated with Lymphatic Filariasis: A Critical Review

Lynne Michelle Zeldenryk, Marion Gray, Richard Speare, Susan Gordon, Wayne Melrose

Research Articles

Effect of a Control Project on Clinical Profiles and Outcomes in Buruli Ulcer: A Before/After Study in Bas-Congo, Democratic Republic of Congo

Delphin Mavinga Phanzu, Patrick Suykerbuyk, Désiré Bofunga B. Imposo, Philippe Ngwala Lukanu, Jean-Bedel Masamba Minuku, Linda F. Lehman, Paul Saunderson, Bouke C. de Jong, Pascal Tshindele Lutumba, Françoise Portaels, Marleen Boelaert

Single Dose Novel Salmonella Vaccine Enhances Resistance against Visceralizing L. major and L. donovani Infection in Susceptible BALB/c Mice

Juliane Schroeder, Najmeeyah Brown, Paul Kaye, Toni Aebischer

Individuals with Le(a+b−) Blood Group Have Increased Susceptibility to Symptomatic Vibrio cholerae O1 Infection

Mohammad Arifuzzaman, Tanvir Ahmed, Mohammad Arif Rahman, Fahima Chowdhury, Rasheduzzaman Rashu, Ashraful I. Khan, Regina C. LaRocque, Jason B. Harris, Taufiqur Rahman Bhuiyan, Edward T. Ryan, Stephen B. Calderwood, Firdausi Qadri

Dengue Virus Type 4 Phylogenetics in Brazil 2011: Looking beyond the Veil

Renato Pereira de Souza, Iray M. Rocco, Adriana Y. Maeda, Carine Spenassatto, Ivani Bisordi, Akemi Suzuki, Vivian R. Silveira, Sarai J. S. Silva, Roberta M. Azevedo, Fernanda M. Tolentino, Jaqueline C. Assis, Margarida G. Bassi, Bibiana P. Dambrós, Gabriela L. Tumioto, Tatiana S. Gregianini, Luiza Terezinha M. Souza, Maria do Carmo S. T. Timenetsky, Cecília L. S. Santos

In Vitro and In Vivo Efficacy of Monepantel (AAD 1566) against Laboratory Models of Human Intestinal Nematode Infections

Lucienne Tritten, Angelika Silbereisen, Jennifer Keiser

Genetic Engineering of Trypanosoma (Dutonella) vivax and In Vitro Differentiation under Axenic Conditions

Simon D'Archivio, Mathieu Medina, Alain Cosson, Nathalie Chamond, Brice Rotureau, Paola Minoprio, Sophie Goyard

Population Dynamics of Aedes aegypti and Dengue as Influenced by Weather and Human Behavior in San Juan, Puerto Rico

Roberto Barrera, Manuel Amador, Andrew J. MacKay

Evaluation of Amoebicidal Potential of Paneth Cell Cryptdin-2 against Entamoeba histolytica

Simran Preet, Sanjay Bharati, Geeta Shukla, Ashwani Koul, Praveen Rishi

Tropheryma whipplei: A Common Bacterium in Rural Senegal

Alpha Kabinet Keita, Hubert Bassene, Adama Tall, Cheikh Sokhna, Pavel Ratmanov, Jean-François Trape, Didier Raoult, Florence Fenollar

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