TconTS-LDs binding to the glycan arrays was determined as described under Methods. Black bars indicate glycans bound by the TconTS-LDs. The presence and absence of the α-helix in TconTS-LD constructs is indicated with “+” and “-“, respectively. Further binding data (S2 Fig) and all glycans on the arrays (S1 Table) are available as Supporting Information.
Homology model of TconTS1 was calculated using the crystal structure of TcTS (PDB: 3b69) as template and the software Yasara. Molecular surface of TconTS1 was calculated using the surface module of Yasara Structure. Illustrated are the parts of TconTS-CD (yellow) and LD (orange), which are in close contact to each other. The α-helix connecting both domains is shown in blue.
Citation: Waespy M, Gbem TT, Elenschneider L, Jeck A-P, Day CJ, Hartley-Tassell L, et al. (2015) Correction: Carbohydrate Recognition Specificity of Trans-sialidase Lectin Domain from Trypanosoma congolense. PLoS Negl Trop Dis 9(12): e0004344. doi:10.1371/journal.pntd.0004344
Published: December 29, 2015
Copyright: © 2015 Waespy et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited