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Correction: Acute Chagas Disease Induces Cerebral Microvasculopathy in Mice

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In Figure 1, the axis for Part C is incorrect. The authors have provided a corrected version here.

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Figure 1. Swiss Webster mice infected with the Y strain of T. cruzi-developed acute CD.

Mice were infected with 104 blood trypomastigote forms, and the following parameters were evaluated in a kinetic study: (A) parasitemia, (B) weight and (C) survival rate. The parasitemia peak occurred at 8 dpi (A). T. cruzi infection induced a significant body weight decrease in a time-dependent manner, starting at 12 dpi. At 22 dpi, the average weight of the NI mice was 31.4±1.9 g, while that of the T. cruzi-infected group was 23.8±2.5 g (B). At 22 dpi, only 20% of the infected animals survived (C). Quantitative data are expressed as the means ± SEM (n  =  20). One-way ANOVA test, p<0.05* and p<0.001***, comparing the infected group at 15 dpi with the NI group; dpi: days post-infection; NI: non-infected.

https://doi.org/10.1371/journal.pntd.0002998.g001

Reference

  1. 1. Nisimura LM, Estato V, de Souza EM, Reis PA, Lessa MA, et al. (2014) Acute Chagas Disease Induces Cerebral Microvasculopathy in Mice. PLoS Negl Trop Dis 8(7): e2998