Figures
Enterotoxigenic Escherichia coli (ETEC) engaging the apical surface of intestinal epithelial cells.
The enterotoxigenic E. coli (ETEC) are a common cause of diarrheal illness in developing countries where these organisms cause hundreds of thousands of deaths annually. Antigenic variability among known ETEC vaccine targets has prompted searches for additional conserved antigens that could be used to prevent ETEC infections. In this issue, Harris et al. explore the use of a highly conserved class of surface proteins known as autotransporters as potential ETEC vaccine constituents. This composite image shows host cell membrane (green), cellular actin (red), and nucleic acid (bacteria and cellular nuclei, blue).
Image Credit: James M. Fleckenstein, Thomas Wong, Michael Whitt (University of Tennessee Health Sciences Center)
Citation: (2011) PLoS Neglected Tropical Diseases Issue Image | Vol. 5(12) November 2011. PLoS Negl Trop Dis 5(12): ev05.i12. https://doi.org/10.1371/image.pntd.v05.i12
Published: November 27, 2011
Copyright: © 2011 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The enterotoxigenic E. coli (ETEC) are a common cause of diarrheal illness in developing countries where these organisms cause hundreds of thousands of deaths annually. Antigenic variability among known ETEC vaccine targets has prompted searches for additional conserved antigens that could be used to prevent ETEC infections. In this issue, Harris et al. explore the use of a highly conserved class of surface proteins known as autotransporters as potential ETEC vaccine constituents. This composite image shows host cell membrane (green), cellular actin (red), and nucleic acid (bacteria and cellular nuclei, blue).
Image Credit: James M. Fleckenstein, Thomas Wong, Michael Whitt (University of Tennessee Health Sciences Center)