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Daniel Yasur-Landau, Charles L. Jaffe, Adi Doron-Faigenboim, Lior David, Gad Baneth
Induction of allopurinol resistance in Leishmania infantum isolated from dogs
www.plosntds.org
www.plosntds.org
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10 0 0 10 360.0566 505.7007 cm
BT
/F7 1 Tf
1 TL
-0.004 Tc
0 0 Td
(10)Tj
ET
Q
q
1 j
1 J
0 w
7.4999 0 0 6.6659 369.5811 510.1228 cm
BT
/F7 1 Tf
1 TL
-0.0053 Tc
0 0 Td
(8)Tj
ET
Q
q
1 j
1 J
0 w
10 0 0 10 375.307 505.7007 cm
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1 TL
-0.004 Tc
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1.8368 0 Td
(log-phase)Tj
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4.2803 0 Td
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(instructions)Tj
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(and)Tj
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(Aldrich,)Tj
3.4469 0 Td
(St.)Tj
1.1962 0 Td
(Louis,)Tj
2.6136 0 Td
(MO\).)Tj
2.3981 0 Td
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1.4514 0 Td
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4.0649 0 Td
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(DE\),)Tj
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1.3833 0 Td
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-31.1751 -1.2983 Td
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(FC-102-1004,)Tj
5.5956 0 Td
(Illumina,)Tj
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-34.1458 -1.2982 Td
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(SBS)Tj
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(FC-401-3001,)Tj
5.6693 0 Td
(Illumina,)Tj
3.8721 0 Td
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2.8459 0 Td
(CA\))Tj
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-34.8205 -1.3039 Td
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3.1351 0 Td
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(\(TruSeq)Tj
3.4753 0 Td
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1.3492 0 Td
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3.1125 0 Td
(Kit)Tj
1.4569 0 Td
(v3,)Tj
1.3776 0 Td
(PE-401-3001,)Tj
5.6069 0 Td
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(CA\),)Tj
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(the)Tj
1.4683 0 Td
(DNA)Tj
2.3755 0 Td
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4.8245 0 Td
(Laboratory)Tj
4.6431 0 Td
(\(St.-Jean-sur-Richelieu,)Tj
9.5583 0 Td
(Canada\).)Tj
-21.6735 -1.2983 Td
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1.9616 0 Td
(reads)Tj
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1.0261 0 Td
(a)Tj
0.652 0 Td
(cleaning)Tj
3.5773 0 Td
(procedure)Tj
4.3142 0 Td
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(the)Tj
1.4684 0 Td
(FASTX)Tj
3.1748 0 Td
(Toolkit)Tj
3.1521 0 Td
(\()Tj
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(http://)Tj
-31.3396 -1.3039 Td
(hannonlab.cshl.edu/fastx_too)Tj
11.7751 0 Td
(lkit/index.html)Tj
0 g
(,)Tj
6.4288 0 Td
(version)Tj
3.1521 0 Td
(0.0.13.2\).)Tj
3.8438 0 Td
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4.388 0 Td
(read)Tj
1.9785 0 Td
(end)Tj
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-33.2841 -1.2982 Td
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2.0976 0 Td
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1.9956 0 Td
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2.9537 0 Td
(scores)Tj
2.6702 0 Td
(under)Tj
2.6192 0 Td
(30)Tj
1.1679 0 Td
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1.7008 0 Td
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2.228 0 Td
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1.474 0 Td
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9.428 0 Td
(and)Tj
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(removal)Tj
3.4753 0 Td
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(than)Tj
2.0296 0 Td
(70%)Tj
1.9276 0 Td
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2.6192 0 Td
(or)Tj
1.0942 0 Td
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1.0261 0 Td
(23,)Tj
1.4003 0 Td
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2.3868 0 Td
(the)Tj
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[()]TJ
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(.)Tj
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0.9695 0 Td
[()12()11( )9()16()22(\n)7()12()]TJ
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3.9004 0 Td
(JPCM5)Tj
3.1408 0 Td
(genome)Tj
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(2.0.0)Tj
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(default)Tj
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(6)Tj
0 g
(].)Tj
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(SNP)Tj
-34.8318 -1.2983 Td
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(\()Tj
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(http://broadinstitute.git)Tj
9.7623 0 Td
(hub.io/picard/)Tj
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(\))Tj
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(2.52\))Tj
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[()]TJ
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(.)Tj
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[()12()11( )9()16()22(\n)7()12()]TJ
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3.1918 0 Td
(3.0)Tj
1.3946 0 Td
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3.5887 0 Td
([)Tj
0.83 0.64 0.02 0 k
(8)Tj
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(].)Tj
ET
Q
q
1 j
1 J
0 w
11.9999 0 0 11.9999 200.0125 125.9716 cm
BT
/F0 1 Tf
1 TL
-0.0033 Tc
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ET
Q
q
1 j
1 J
0 w
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BT
/F7 1 Tf
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ET
Q
q
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1 J
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BT
/F7 1 Tf
1 TL
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(50)Tj
ET
Q
q
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1 J
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(HSD)Tj
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ET
Q
q
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1 J
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BT
/F7 1 Tf
1 TL
-0.0053 Tc
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(50)Tj
ET
Q
q
1 j
1 J
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BT
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1 TL
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ET
Q
q
1 j
1 J
0 w
576 737.1 m
36 737.1 l
36 737.6 l
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f*
36 741.2598 183.2882 23.6976 re
W* n
q
183.2315 0 0 23.6409 36 741.3165 cm
q
/I0 Do
Q
Q
Q
q
0 0 612 792 re
W* n
1 j
1 J
0 w
7.9999 0 0 7.9999 395.8299 745.7952 cm
BT
/F0 1 Tf
1 TL
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(Allopurino)Tj
4.3512 0 Td
(l)Tj
0.4323 0 Td
(resistance)Tj
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(induction)Tj
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(Leishmani)Tj
4.4717 0 Td
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ET
Q
q
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1 J
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576 48.0002 l
576 47.5002 l
36 47.5002 l
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163.5591 34.9228 m
317.7071 34.9228 l
h
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7.9999 0 0 7.9999 36 36 cm
BT
/F0 1 Tf
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(PLOS)Tj
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%!PS-AdobeFont-1.0
11 dict begin
/FontName /TeX_CM_Maths_Italic def
/FontType 1 def
/FontBBox {-31 -239 1041 750} readonly def
/FontMatrix [0.001 0 0 0.001 0 0] readonly def
/PaintType 0 def
/FontInfo 8 dict dup begin
/FullName (TeX_CM_Maths_Italic) readonly def
/BaseFontName (TeX_CM_Maths_Italic) def
end def
/Encoding 256 array
0 1 255 {1 index exch /.notdef put} for
dup 0 /C0 put
dup 1 /C1 put
dup 2 /C2 put
dup 3 /C3 put
dup 4 /C4 put
dup 5 /C5 put
dup 6 /C6 put
dup 7 /C7 put
dup 8 /C8 put
dup 9 /C9 put
dup 10 /C10 put
dup 11 /C11 put
dup 12 /C12 put
dup 13 /C13 put
dup 14 /C14 put
dup 15 /C15 put
dup 16 /C16 put
dup 17 /C17 put
dup 18 /C18 put
dup 19 /C19 put
dup 20 /C20 put
dup 21 /C21 put
dup 22 /C22 put
dup 23 /C23 put
dup 24 /C24 put
dup 25 /C25 put
dup 26 /C26 put
dup 27 /C27 put
dup 28 /C28 put
dup 29 /C29 put
dup 30 /C30 put
dup 31 /C31 put
dup 32 /space put
dup 33 /exclam put
dup 34 /quotedbl put
dup 35 /numbersign put
dup 36 /dollar put
dup 37 /percent put
dup 38 /ampersand put
dup 39 /quoteright put
dup 40 /parenleft put
dup 41 /parenright put
dup 42 /asterisk put
dup 43 /plus put
dup 44 /comma put
dup 45 /hyphen put
dup 46 /period put
dup 47 /slash put
dup 48 /zero put
dup 49 /one put
dup 50 /two put
dup 51 /three put
dup 52 /four put
dup 53 /five put
dup 54 /six put
dup 55 /seven put
dup 56 /eight put
dup 57 /nine put
dup 58 /colon put
dup 59 /semicolon put
dup 60 /less put
dup 61 /equal put
dup 62 /greater put
dup 63 /question put
dup 64 /at put
dup 65 /A put
dup 66 /B put
dup 67 /C put
dup 68 /D put
dup 69 /E put
dup 70 /F put
dup 71 /G put
dup 72 /H put
dup 73 /I put
dup 74 /J put
dup 75 /K put
dup 76 /L put
dup 77 /M put
dup 78 /N put
dup 79 /O put
dup 80 /P put
dup 81 /Q put
dup 82 /R put
dup 83 /S put
dup 84 /T put
dup 85 /U put
dup 86 /V put
dup 87 /W put
dup 88 /X put
dup 89 /Y put
dup 90 /Z put
dup 91 /bracketleft put
dup 92 /backslash put
dup 93 /bracketright put
dup 94 /asciicircum put
dup 95 /underscore put
dup 96 /quoteleft put
dup 97 /a put
dup 98 /b put
dup 99 /c put
dup 100 /d put
dup 101 /e put
dup 102 /f put
dup 103 /g put
dup 104 /h put
dup 105 /i put
dup 106 /j put
dup 107 /k put
dup 108 /l put
dup 109 /m put
dup 110 /n put
dup 111 /o put
dup 112 /p put
dup 113 /q put
dup 114 /r put
dup 115 /s put
dup 116 /t put
dup 117 /u put
dup 118 /v put
dup 119 /w put
dup 120 /x put
dup 121 /y put
dup 122 /z put
dup 123 /braceleft put
dup 124 /bar put
dup 125 /braceright put
dup 126 /asciitilde put
dup 127 /Euro put
readonly def
currentdict end
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