Neutrophil Extracellular Traps are Involved in the Innate Immune Response to Infection with Leptospira
Fig 8
Renal histopathology at the beginning of the leptospiruric phase.
C57BL/6J male weanlings received 0.25 mg of non-immune rat IgG or purified anti-Ly6G rat mAb1A8 every 48 h and 200 μL 1x107/mL pathogenic Leptospira interrogans serovar Copenhageni (LIC). Representative hematoxylin and eosin (H&E) stained kidney sections from 14 days post-infection showing histology (A) and inflammation score (B) from uninfected mAb1A8-treated mice, rat IgG-treated LIC-infected mice, and mAb1A8-treated LIC-infected mice (n = 6–10 mice). Scale bar indicates 50 μm.