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Cathelicidin-like Helminth Defence Molecules (HDMs): Absence of Cytotoxic, Anti-microbial and Anti-protozoan Activities Imply a Specific Adaptation to Immune Modulation

Figure 5

Mammalian, but not helminth, peptides induce the release of LDH from macrophages.

RAW macrophages were incubated with peptides for 1 h at 37°C. The release of LDH by cells was measured and expressed as the percentage of LDH released after treatment of cells with lysis buffer (regarded as 100%). Data shown are the means ± SEM of triplicate samples and representative of three independent experiments.

Figure 5

doi: https://doi.org/10.1371/journal.pntd.0002307.g005