Schistosoma japonicum Soluble Egg Antigens Attenuate Invasion in a First Trimester Human Placental Trophoblast Model
Figure 2
Production of pro-inflammatory cytokines/chemokines are upregulated by SEA in HTR8 cells.
The first-trimester cell line model, HTR8/SVneo, was treated with SEA (25 ug/ml) for 24 h. Media from all treatment conditions was collected and measured for cytokine expression. A and B) IL-6 & IL-8 production are both increased after SEA exposure. P = 0.01 and 0.02, respectively, n = 9 C) MCP1 production is increased after SEA treatment. P<0.04, n = 13 pairs of HTR8 cells cultured +/− SEA.