Induction of CD4+CD25+FOXP3+ Regulatory T Cells during Human Hookworm Infection Modulates Antigen-Mediated Lymphocyte Proliferation
Figure 2
Flow cytometric analysis of surface markers (CTLA-4 and GITR) and cytokines (IL-10, TGF-β, and IL-17) in CD4+CD25+FOXP3+ regulatory T cells in Necator-infected and non-infected donors (n = 10 for both groups).
Results were expressed as absolute numbers of cells expressing (A) CTLA-4, (B) GITR, (C) IL-10, (D) TGF-β, and (E) IL-17. Absolute numbers (cells/mm3) are indicated on Y-axis and lines represent median. Statistical differences were detected using Mann-Whitney U test and are indicated on the graphs with significant P values.