Schistosoma mansoni Tegument Protein Sm29 Is Able to Induce a Th1-Type of Immune Response and Protection against Parasite Infection
Figure 5
Transcript level changes in selected genes of S. mansoni worms recovered from mice vaccinated with rSm29.
The figure shows real-time RT-PCR validation experiment for six genes down-regulated in S. mansoni worms recovered from rSm29+adjuvant immunized mice (black bars) compared to worms from PBS+adjuvant injected control mice (white bars). The selected genes were: CD36-CD36-like class B scavenger receptor [S. mansoni]; Sm23-Sm23 kDa integral membrane protein [S. mansoni]; Sm14-Fatty acid-binding protein Sm14 [S. mansoni]; Superox-Superoxide dismutase [S. mansoni]; TGF-β RIP-TGF-β receptor interacting protein 1 [C. sinensis]; B-cell RAP-B-cell receptor-associated protein-like protein [S. mansoni]. Statistically significant differences of vaccinated mice compared to PBS+adjuvant control group is denoted by one asterisk (p<0.03).