A Simplified 4-Site Economical Intradermal Post-Exposure Rabies Vaccine Regimen: A Randomised Controlled Comparison with Standard Methods

Mary J. Warrell; Anna Riddell; Ly-Mee Yu; Judith Phipps; Linda Diggle; Hervé Bourhy; Jonathan J. Deeks; Anthony R. Fooks; Laurent Audry; Sharon M. Brookes; François-Xavier Meslin; Richard Moxon; Andrew J. Pollard; David A. Warrell

doi:10.1371/journal.pntd.0000224

Loading metrics

Open Access

Peer-reviewed

Research Article

A Simplified 4-Site Economical Intradermal Post-Exposure Rabies Vaccine Regimen: A Randomised Controlled Comparison with Standard Methods

Mary J. Warrell,

Affiliation The Oxford Vaccine Group, Centre for Clinical Vaccinology & Tropical Medicine University of Oxford, Churchill Hospital, Oxford, United Kingdom
⨯
Anna Riddell,

Affiliation The Oxford Vaccine Group, Centre for Clinical Vaccinology & Tropical Medicine University of Oxford, Churchill Hospital, Oxford, United Kingdom
⨯
Ly-Mee Yu,

Affiliation Centre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom
⨯
Judith Phipps,

Affiliation The Oxford Vaccine Group, Centre for Clinical Vaccinology & Tropical Medicine University of Oxford, Churchill Hospital, Oxford, United Kingdom
⨯
Linda Diggle,

Affiliation The Oxford Vaccine Group, Centre for Clinical Vaccinology & Tropical Medicine University of Oxford, Churchill Hospital, Oxford, United Kingdom
⨯
Hervé Bourhy,

Affiliation UPRE Lyssavirus Dynamics and Host Adaptation, WHO Collaborating Centre for Reference and Research on Rabies, Institut Pasteur, Paris, France
⨯
Jonathan J. Deeks,

Affiliation Centre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom
⨯
Anthony R. Fooks,

Affiliation Rabies and Wildlife Zoonoses Group, WHO Collaborating Centre for the Characterization of Rabies and Rabies-Related Viruses, Veterinary Laboratories Agency, Weybridge, United Kingdom
⨯
Laurent Audry,

Affiliation UPRE Lyssavirus Dynamics and Host Adaptation, WHO Collaborating Centre for Reference and Research on Rabies, Institut Pasteur, Paris, France
⨯
Sharon M. Brookes,

Affiliation Rabies and Wildlife Zoonoses Group, WHO Collaborating Centre for the Characterization of Rabies and Rabies-Related Viruses, Veterinary Laboratories Agency, Weybridge, United Kingdom
⨯
François-Xavier Meslin,

Affiliation Zoonoses and VPH, Department of Food Safety, Zoonoses and Foodborne Diseases, World Health Organization, Geneva, Switzerland
⨯
Richard Moxon,

Affiliation The Oxford Vaccine Group, Centre for Clinical Vaccinology & Tropical Medicine University of Oxford, Churchill Hospital, Oxford, United Kingdom
⨯
Andrew J. Pollard,

Affiliation The Oxford Vaccine Group, Centre for Clinical Vaccinology & Tropical Medicine University of Oxford, Churchill Hospital, Oxford, United Kingdom
⨯
David A. Warrell

* E-mail: mary.warrell@ndm.ox.ac.uk

Affiliation The Oxford Vaccine Group, Centre for Clinical Vaccinology & Tropical Medicine University of Oxford, Churchill Hospital, Oxford, United Kingdom
⨯

A Simplified 4-Site Economical Intradermal Post-Exposure Rabies Vaccine Regimen: A Randomised Controlled Comparison with Standard Methods

Mary J. Warrell,
Anna Riddell,
Ly-Mee Yu,
Judith Phipps,
Linda Diggle,
Hervé Bourhy,
Jonathan J. Deeks,
Anthony R. Fooks,
Laurent Audry,
Sharon M. Brookes

Published: April 23, 2008
https://doi.org/10.1371/journal.pntd.0000224

Reader Comments

Post a new comment on this article

Note Regarding Symbol Display

Posted by plosntds_team on 23 Jul 2008 at 18:09 GMT

Symbols represent: • Group A 4-site; ▴ Group B 8-site; x Group D 2-site; □ Group E IM.
http://plosntds.org/article/info:doi/10.1371/journal.pntd.0000224#pntd-0000224-g004

Some browsers are unable to read all the symbols. Group B, 8-site is represented by triangles in Figures 2 and 4.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Vaccines
Is the Subject Area "Vaccines" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Rabies
Is the Subject Area "Rabies" applicable to this article?

Thanks for your feedback.
Antigens
Is the Subject Area "Antigens" applicable to this article?

Thanks for your feedback.
Vaccine development
Is the Subject Area "Vaccine development" applicable to this article?

Thanks for your feedback.
Post-exposure prophylaxis
Is the Subject Area "Post-exposure prophylaxis" applicable to this article?

Thanks for your feedback.
Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
Vaccination and immunization
Is the Subject Area "Vaccination and immunization" applicable to this article?

Thanks for your feedback.

A Simplified 4-Site Economical Intradermal Post-Exposure Rabies Vaccine Regimen: A Randomised Controlled Comparison with Standard Methods

A Simplified 4-Site Economical Intradermal Post-Exposure Rabies Vaccine Regimen: A Randomised Controlled Comparison with Standard Methods

Reader Comments

Post Your Discussion Comment

Why should this posting be reviewed?

Thank You!

Note Regarding Symbol Display

Posted by plosntds_team on 23 Jul 2008 at 18:09 GMT