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The nematode EcR era begins...

Posted by LloydG on 11 Mar 2010 at 00:08 GMT

Very interesting work, especially the functional data.

Feb/Mar 2010 seems to have ushered in the era of the nematode EcR. Four papers have appeared over the past four weeks, each describing an EcR ortholog (and in some cases, the RXR as well) from a different nematode species – two from Clade III, and two from Clade V. In addition to this paper, I am aware of:

Parihar et al. (2010) The genome of the nematode Pristionchus pacificus encodes putative homologs of RXR/Usp and EcR. Gen. Comp. Endocrinol. (in press). doi:10.1016/j.ygcen.2010.02.005

Shea et al. (2010) An EcR homolog from the filarial parasite, Dirofilaria immitis requires a ligand-activated partner for transactivation. Mol. Biochem. Parasitol., in press. doi:10.1016/j.molbiopara.2010.02.002

Graham et al. (2010) An ortholog of the ecdysone receptor protein (EcR) from the parasitic nematode Haemonchus contortus. Mol. Biochem. Parasitol., in press. Pre-publication article at, doi:10.1016/j.molbiopara.2010.03.003 (not yet live).

No competing interests declared.

RE: The nematode EcR era begins...

LloydG replied to LloydG on 11 Mar 2010 at 00:16 GMT

Sorry, the current URL for that last paper should be (no comma).

No competing interests declared.