The paper by Ganiel et al [1] reports that cerebral toxoplasmosis can mimick subacute meningitis, however the afforded evidence is insuffcient to conclude about that. In this series most of patients did not had cerebral imaging doing impossible to determine if there were only meningitis and/or cerebral mass. Co-infection can be common on final stages of HIV infection and other neuropportunistic infections should be considered (aside criptococosis and tuberculosis) such as CMV, lymphoma and HIV encephalitis [2]. If cerebral imaging is not available, empirical treatment for toxoplasmosis should be considered as authors recommend, when high IgG anti "Toxoplasma" titers are present, but other conditions should also be considered. The results in this indonensian series showed the need to improve the health care in that country for HIV patients and the need to include more analytical tests that help to identify not only toxoplasmosis but other treatable neuropportunistic conditions.

1. Ganiem AR, Dian S, Indriati A, Chaidir L, Wisaksana R, et al. (2013) Cerebral Toxoplasmosis Mimicking subacute Meningitis in HIV-Infected Patients; a
Cohort Study from Indonesia. PLoS Negl Trop Dis 7(1): e1994. doi:10.1371/journal.pntd.0001994
2. Cardona N, Basto N, Parra B, Zea AF, Pardo CA, Bonelo A, Gomez-Marin JE. Detection of Toxoplasma DNA in the peripheral blood of HIV-positive patients with neuropportunistic infections by a real time PCR assay. Journal Neuroparasitology, 2011; 2: Article ID N110402, 6 pages doi:10.4303/jnp/N110402.