TY - JOUR T1 - Effect of Schistosomiasis and Soil-Transmitted Helminth Infections on Physical Fitness of School Children in Côte d'Ivoire A1 - Müller, Ivan A1 - Coulibaly, Jean T. A1 - Fürst, Thomas A1 - Knopp, Stefanie A1 - Hattendorf, Jan A1 - Krauth, Stefanie J. A1 - Stete, Katarina A1 - Righetti, Aurélie A. A1 - Glinz, Dominik A1 - Yao, Adrien K. A1 - Pühse, Uwe A1 - N'Goran, Eliézer K. A1 - Utzinger, Jürg Y1 - 2011/07/19 N2 - Author Summary The burden of parasitic worm infections is considerable, particularly in developing countries. It is acknowledged that parasitic worm infections negatively impact on children's school performance and physical development. A deeper understanding of these linkages is important for updating burden of disease measures. We investigated the relationship between worm infection status and physical fitness of 156 school children from Côte d'Ivoire and controlled for potential confounding of Plasmodium infection (the causative agent of malaria) and environmental parameters (temperature and humidity). Children were diagnosed for parasitic worm and Plasmodium infections, examined by a physician, and participated in a 20 m shuttle run test to assess their maximal oxygen uptake (VO2 max) as a proxy for physical fitness. Most of the children had parasitic worms and a Plasmodium infection. Nevertheless, their physical fitness was excellent (average VO2 max: 52.7 ml kg−1 min−1). The level of VO2 max was only influenced by sex and age, but not by parasitic worms and Plasmodium infections. In future studies, the dynamics of children's physical performance should be assessed before and after control interventions, including the assessment of blood hemoglobin, hematocrit, and nutritional indicators to determine whether physical fitness in worm- and Plasmodium-infected individuals can be further improved. JF - PLOS Neglected Tropical Diseases JA - PLOS Neglected Tropical Diseases VL - 5 IS - 7 UR - https://doi.org/10.1371/journal.pntd.0001239 SP - e1239 EP - PB - Public Library of Science M3 - doi:10.1371/journal.pntd.0001239 ER -