About the Authors

Matthew H. Stremlau

Contributed equally to this work with: Matthew H. Stremlau, Kristian G. Andersen

stremlau@gmail.com (MHS); andersen@broadinstitute.org (KGA); pardis@broadinstitute.org (PCS); happic@run.edu.ng (CTH)

Affiliations FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America, Broad Institute, Cambridge, Massachusetts, United States of America

Kristian G. Andersen

Contributed equally to this work with: Matthew H. Stremlau, Kristian G. Andersen

stremlau@gmail.com (MHS); andersen@broadinstitute.org (KGA); pardis@broadinstitute.org (PCS); happic@run.edu.ng (CTH)

Affiliations FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America, Broad Institute, Cambridge, Massachusetts, United States of America

Onikepe A. Folarin

Affiliations Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria, Department of Biological Sciences, College of Natural Sciences, Redeemer's University, Redemption City, Ogun State, Nigeria

Jessica N. Grove

Affiliation Department of Microbiology and Immunology, Tulane University, New Orleans, Louisiana, United States of America

Ikponmwonsa Odia

Affiliation Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria

Philomena E. Ehiane

Affiliation Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria

Omowunmi Omoniwa

Affiliation Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria

Omigie Omoregie

Affiliation Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria

Pan-Pan Jiang

Affiliations FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America, Broad Institute, Cambridge, Massachusetts, United States of America

Nathan L. Yozwiak

Affiliations FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America, Broad Institute, Cambridge, Massachusetts, United States of America

Christian B. Matranga

Affiliation Broad Institute, Cambridge, Massachusetts, United States of America

Xiao Yang

Affiliation Broad Institute, Cambridge, Massachusetts, United States of America

Stephen K. Gire

Affiliations FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America, Broad Institute, Cambridge, Massachusetts, United States of America

Sarah Winnicki

Affiliations FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America, Broad Institute, Cambridge, Massachusetts, United States of America

Ridhi Tariyal

Affiliation Broad Institute, Cambridge, Massachusetts, United States of America

Stephen F. Schaffner

Affiliation Broad Institute, Cambridge, Massachusetts, United States of America

Peter O. Okokhere

Affiliation Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria

Sylvanus Okogbenin

Affiliation Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria

George O. Akpede

Affiliation Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria

Danny A. Asogun

Affiliation Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria

Dennis E. Agbonlahor

Affiliation Lahor Research Laboratories and Medical Centre, Benin City, Edo State, Nigeria

Peter J. Walker

Affiliation CSIRO Animal, Food and Health Sciences, Australian Animal Health Laboratory, Geelong, Australia

Robert B. Tesh

Affiliation Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

Joshua Z. Levin

Affiliation Broad Institute, Cambridge, Massachusetts, United States of America

Robert F. Garry

Affiliation Department of Microbiology and Immunology, Tulane University, New Orleans, Louisiana, United States of America

Pardis C. Sabeti

stremlau@gmail.com (MHS); andersen@broadinstitute.org (KGA); pardis@broadinstitute.org (PCS); happic@run.edu.ng (CTH)

‡These authors jointly supervised this work

Affiliations FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America, Broad Institute, Cambridge, Massachusetts, United States of America, Department of Immunology and Infectious Disease, Harvard School of Public Health, Boston, Massachusetts, United States of America

Christian T. Happi

stremlau@gmail.com (MHS); andersen@broadinstitute.org (KGA); pardis@broadinstitute.org (PCS); happic@run.edu.ng (CTH)

‡These authors jointly supervised this work

Affiliations Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria, Department of Biological Sciences, College of Natural Sciences, Redeemer's University, Redemption City, Ogun State, Nigeria

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MHS KGA PCS CTH. Performed the experiments: MHS RT OAF IO PEE OOmon OOmor JNG NLY PPJ. Analyzed the data: MHS KGA JNG PPJ. Contributed reagents/materials/analysis tools: KGA CBM XY SKG SW RT POO SO GOA DAA DEA JZL. Wrote the paper: MHS KGA SFS PJW RBT RFG PCS. Developed computational pipeline: KGA. Sample collection and processing: MHS RT OAF IO PEE OOmon OOmor.