About the Authors

Teresa G. Martins

Affiliations Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Gabriela Trigo

Affiliations Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal, Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, University of Minho, Braga, Portugal

Alexandra G. Fraga

Affiliations Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

José B. Gama

Affiliations Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Adhemar Longatto-Filho

Affiliations Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal, Laboratory of Medical Investigation 14, Faculty of Medicine of University of São Paulo, São Paulo, Brazil, Molecular Oncology Research Center, Barretos, São Paulo, Brazil

Margarida Saraiva

Affiliations Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Manuel T. Silva

† Deceased.

Affiliation Institute for Molecular and Cell Biology, Porto, Portugal

António G. Castro

Affiliations Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Jorge Pedrosa

jpedrosa@ecsaude.uminho.pt

Affiliations Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TGM MS MTS AGC JP. Performed the experiments: TGM GT AGF JBG ALF. Analyzed the data: TGM ALF MS MTS AGC JP. Contributed reagents/materials/analysis tools: TGM MS MTS AGC JP. Wrote the paper: TGM AGF ALF MS MTS AGC JP.