About the Authors

Ross A. Paveley

Affiliation Department of Infection and Immunity, London School of Hygiene and Tropical Medicine, London, United Kingdom

Nuha R. Mansour

Affiliation Department of Infection and Immunity, London School of Hygiene and Tropical Medicine, London, United Kingdom

Irene Hallyburton

Affiliation Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom

Leo S. Bleicher

Affiliation Accelrys Inc., San Diego, California, United States of America

Alex E. Benn

Affiliation Accelrys Ltd, Cambridge, United Kingdom

Ivana Mikic

Affiliation Accelrys Inc., San Diego, California, United States of America

Alessandra Guidi

Affiliation Department of Infection and Immunity, London School of Hygiene and Tropical Medicine, London, United Kingdom

Ian H. Gilbert

Affiliation Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom

Andrew L. Hopkins

Affiliation Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom

Quentin D. Bickle

quentin.bickle@lshtm.ac.uk

Affiliation Department of Infection and Immunity, London School of Hygiene and Tropical Medicine, London, United Kingdom

Competing Interests

The authors have read the journal's policy and have the following conflicts: LSB, AEB and IM receive a salary from Accelrys, who markets Pipeline Pilot as commercial software, in which the authors designed their analysis protocols. This does not alter the authors' adherence to all PLoS Neglected Tropical Diseases policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: QDB ALH RAP. Performed the experiments: RAP NRM AG. Analyzed the data: RAP QDB NRM. Contributed reagents/materials/analysis tools: IHG IH LSB AEB IM. Wrote the paper: RAP QDB.