About the Authors

Ruklanthi de Alwis

Affiliation Department of Microbiology and Immunology, and the Southeast Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Martina Beltramello

Affiliation Institute for Research in Biomedicine, Bellinzona, Switzerland

William B. Messer

Affiliation Department of Microbiology and Immunology, and the Southeast Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Soila Sukupolvi-Petty

Affiliation Departments of Medicine, Molecular Microbiology, Pathology and Immunology, and the Midwest Regional Center for Biodefense and Emerging Infectious Diseases Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

Wahala M. P. B. Wahala

Affiliation Department of Microbiology and Immunology, and the Southeast Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Annette Kraus

Affiliation Department of Microbiology and Immunology, and the Southeast Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Nicholas P. Olivarez

Affiliation Department of Microbiology and Immunology, and the Southeast Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Quang Pham

Affiliation Department of Microbiology and Immunology, and the Southeast Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

James Brian

Affiliation Departments of Medicine, Molecular Microbiology, Pathology and Immunology, and the Midwest Regional Center for Biodefense and Emerging Infectious Diseases Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

Wen-Yang Tsai

Affiliation Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States of America

Wei-Kung Wang

Affiliation Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States of America

Scott Halstead

Affiliation Pediatric Dengue Vaccine Initiative, International Vaccine Institute, Seoul, Korea

Srisakul Kliks

Affiliation Pediatric Dengue Vaccine Initiative, International Vaccine Institute, Seoul, Korea

Michael S. Diamond

Affiliation Departments of Medicine, Molecular Microbiology, Pathology and Immunology, and the Midwest Regional Center for Biodefense and Emerging Infectious Diseases Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

Ralph Baric

Affiliation Department of Microbiology and Immunology, and the Southeast Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Antonio Lanzavecchia

Affiliation Institute for Research in Biomedicine, Bellinzona, Switzerland

Federica Sallusto

Affiliation Institute for Research in Biomedicine, Bellinzona, Switzerland

Aravinda M. de Silva

desilva@med.unc.edu

Affiliation Department of Microbiology and Immunology, and the Southeast Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RdA MB WBM S-SP WMPBW AK NPO QP JB W-YT W-KW SH SK MSD RB AL FS AMdS. Performed the experiments: RdA MB WBM S-SP WMPBW AK NPO QP JB W-YT W-KW. Analyzed the data: RdA MB WBM S-SP WMPBW AK NPO QP JB W-YT W-KW SH SK MSD RB AL FS AMdS. Contributed reagents/materials/analysis tools: AK MSD RB AL FS. Wrote the paper: RdA MB QP SH SK MSD RB AL FS AMdS.