About the Authors

Joshua M. Costin

Affiliation Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, United States of America

Ekachai Jenwitheesuk

Address Current address: National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Klong Luang, Thailand

Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America

Shee-Mei Lok

Address Current address: Program in Emerging Infectious Disease, Duke –NUS Graduate Medical School, and Department of Biological Sciences, National University of Singapore, Singapore, Singapore

Affiliation Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America

Elizabeth Hunsperger

Affiliation Dengue Branch, Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico

Kelly A. Conrads

Affiliation FortéBio, Incorporated, Menlo Park, California, United States of America

Krystal A. Fontaine

Address Current address: Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, United States of America

Affiliation Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, United States of America

Craig R. Rees

Address Current address: School of Public Health, University of Florida, Gainesville, Florida, United States of America

Affiliation Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, United States of America

Michael G. Rossmann

Affiliation Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America

Sharon Isern

Affiliation Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, United States of America

Ram Samudrala

ram@compbio.washington.edu (RS); smichael@fgcu.edu (SFM)

Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America

Scott F. Michael

ram@compbio.washington.edu (RS); smichael@fgcu.edu (SFM)

Affiliation Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, United States of America

Competing Interests

The authors acknowledge that Florida Gulf Coast University, Tulane University, and the University of Washington have submitted patent applications covering the peptides described in this manuscript.

Author Contributions

Conceived and designed the experiments: JMC EJ SI RS SFM. Performed the experiments: JMC EJ SML EH KAC KAF CRR. Analyzed the data: JMC EJ SML KAF MGR SI RS SFM. Contributed reagents/materials/analysis tools: JMC EJ SML MGR SI RS SFM. Wrote the paper: JMC SFM.