About the Authors

Elizabeth R. Sharlow

Affiliations University of Pittsburgh Drug Discovery Institute and the Pittsburgh Molecular Library Screening Center, Pittsburgh, Pennsylvania, United States of America, Departments of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

David Close

Affiliation University of Pittsburgh Drug Discovery Institute and the Pittsburgh Molecular Library Screening Center, Pittsburgh, Pennsylvania, United States of America

Tongying Shun

Affiliation University of Pittsburgh Drug Discovery Institute and the Pittsburgh Molecular Library Screening Center, Pittsburgh, Pennsylvania, United States of America

Stephanie Leimgruber

Affiliation University of Pittsburgh Drug Discovery Institute and the Pittsburgh Molecular Library Screening Center, Pittsburgh, Pennsylvania, United States of America

Robyn Reed

Affiliation University of Pittsburgh Drug Discovery Institute and the Pittsburgh Molecular Library Screening Center, Pittsburgh, Pennsylvania, United States of America

Gabriela Mustata

Affiliation Department of Computational Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Peter Wipf

Affiliations University of Pittsburgh Drug Discovery Institute and the Pittsburgh Molecular Library Screening Center, Pittsburgh, Pennsylvania, United States of America, Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Jacob Johnson

Affiliation Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America

Michael O'Neil

Affiliation Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America

Max Grögl

Affiliation Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America

Alan J. Magill

Affiliation Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America

John S. Lazo

lazo@pitt.edu

Affiliations University of Pittsburgh Drug Discovery Institute and the Pittsburgh Molecular Library Screening Center, Pittsburgh, Pennsylvania, United States of America, Departments of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ERS JJ MO MG AJM JSL. Performed the experiments: ERS DC SL RR. Analyzed the data: ERS DC TS SL RR GM PW JJ MO MG AJM JSL. Contributed reagents/materials/analysis tools: ERS PW JJ MO MG AJM JSL. Wrote the paper: ERS DC TS SL RR GM MO MG AJM JSL.