About the Authors

Ernest J. Mui, Michael Kirisits, Susan R. Liu, Rima McLeod
Department of Ophthalmology and Visual Science, University of Chicago, Chicago, Illinois, United States of America

Guy A. Schiehser, Honghue Hsu, David P. Jacobus
Jacobus Pharmaceutical Company, Inc., Princeton, New Jersey, United States of America

Wilbur K. Milhous
Walter Reed Army Institute for Research, Silver Spring, Maryland, United States of America

Craig W. Roberts
Department of Immunology, Strathclyde Institute for Biomedical Sciences, University of Strathclyde, Scotland, United Kingdom

Stephen Muench, David Rice
Krebs Institute for Biomolecular Research, Department of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, England, United Kingdom

J. P. Dubey
United States Department of Agriculture, Agricultural Research Services, Animal and Natural Resources Institute, Animal Parasitic Diseases Laboratory, Beltsville, Maryland, United States of America

Joseph W. Fowble, Pradipsinh K. Rathod
Department of Chemistry, University of Washington, Seattle, Washington, United States of America

Sherry F. Queener
Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Rima McLeod
Department of Pediatrics, Committee on Molecular Medicines, Genetics, and Immunology and The College, University of Chicago, Chicago, Illinois, United States of America

Corresponding Author

rmcleod@midway.uchicago.edu

Competing Interests

DPJ and Jacobus Pharmaceutical Company are progressing JPC-2056 for the treatment of malaria. The other authors declare that they have no competing financial interests.

Author Contributions

Conceived and designed the experiments: RM PR CR SM GS WM DR JD JF SQ. Performed the experiments: SM EM GS HH MK JD JF SQ SL. Analyzed the data: RM PR CR SM EM GS WM HH DR MK JD JF SQ SL. Contributed reagents/materials/analysis tools: RM PR GS WM JD SQ. Wrote the paper: RM PR CR SM EM GS WM HH DR MK JD JF SQ SL.