About the Authors

Dirk F. van Helden

dirk.vanhelden@newcastle.edu.au

Affiliations School of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia

Paul A. Thomas

Affiliations School of Medicine, University of Queensland, Brisbane, Queensland, Australia, Department of Nuclear Medicine, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia

Peter J. Dosen

Affiliation School of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia

Mohammad S. Imtiaz

Affiliation School of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia

Derek R. Laver

Affiliation School of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia

Geoffrey K. Isbister

Affiliations School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia, Department of Clinical Toxicology and Pharmacology, Calvary Mater Newcastle, Waratah, New South Wales, Australia

Competing Interests

I have read the journal's policy and have the following conflicts: DFvH has an Australian use patent for GTNO. This does not alter our adherence to all PLOS policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DFvH PAT GKI. Performed the experiments: PJD. Analyzed the data: DFvH. Contributed reagents/materials/analysis tools: MSI DRL. Wrote the paper: DFvH GKI.