Caspase Dependent Programmed Cell Death in Developing Embryos: A Potential Target for Therapeutic Intervention against Pathogenic Nematodes

Alok Das Mohapatra; Sunil Kumar; Ashok Kumar Satapathy; Balachandran Ravindran

doi:10.1371/journal.pntd.0001306

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Open Access

Peer-reviewed

Research Article

Caspase Dependent Programmed Cell Death in Developing Embryos: A Potential Target for Therapeutic Intervention against Pathogenic Nematodes

Alok Das Mohapatra,

Affiliation Department of Infectious Disease Biology, Institute of Life Sciences, DBT, Ministry of Science and Technology, Government of India, Bhubaneswar, India
⨯
Sunil Kumar,

Affiliation Department of Infectious Disease Biology, Institute of Life Sciences, DBT, Ministry of Science and Technology, Government of India, Bhubaneswar, India
⨯
Ashok Kumar Satapathy,

Affiliation Department of Applied Immunology, Regional Medical Research Centre, Indian Council of Medical Research, Government of India, Bhubaneswar, India
⨯
Balachandran Ravindran

* E-mail: ravindran8@gmail.com

Affiliation Department of Infectious Disease Biology, Institute of Life Sciences, DBT, Ministry of Science and Technology, Government of India, Bhubaneswar, India
⨯

Caspase Dependent Programmed Cell Death in Developing Embryos: A Potential Target for Therapeutic Intervention against Pathogenic Nematodes

Alok Das Mohapatra,
Sunil Kumar,
Ashok Kumar Satapathy,
Balachandran Ravindran

Published: September 13, 2011
https://doi.org/10.1371/journal.pntd.0001306

About the Authors

Alok Das Mohapatra

Affiliation Department of Infectious Disease Biology, Institute of Life Sciences, DBT, Ministry of Science and Technology, Government of India, Bhubaneswar, India

Sunil Kumar

Affiliation Department of Infectious Disease Biology, Institute of Life Sciences, DBT, Ministry of Science and Technology, Government of India, Bhubaneswar, India

Ashok Kumar Satapathy

Affiliation Department of Applied Immunology, Regional Medical Research Centre, Indian Council of Medical Research, Government of India, Bhubaneswar, India

Balachandran Ravindran

* E-mail: ravindran8@gmail.com

Affiliation Department of Infectious Disease Biology, Institute of Life Sciences, DBT, Ministry of Science and Technology, Government of India, Bhubaneswar, India

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BR. Performed the experiments: ADM. Analyzed the data: ADM AKS BR. Wrote the paper: ADM BR. Performed the molecular docking study: SK.

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Apoptosis
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Embryos
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Parasitic diseases
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Nematode infections
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Helminths
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Mitochondria
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Embryogenesis
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Flow cytometry
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