Dementia is a growing problem, with 46.8 million cases worldwide in 2015 and over 131.5 million people estimated to be living with the condition by 2050. With 71% of those cases predicted to be in low- or middle-income countries, it is also a global problem. In this month's Editorial, we highlight the need for research informing dementia from all angles: identifying risk factors, understanding variation in types, evaluating interventions, developing diagnosis and screening strategies, and exploring its societal impact. We invite submission of research studies to PLOS Medicine for our Special Issue on Dementia to be published in early 2017, with Drs. Carol Brayne and Bruce Miller serving as Guest Editors.
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Editorial
Dementia across the Lifespan and around the Globe—Pathophysiology, Prevention, Treatment, and Societal Impact: A Call for Papers
PLOS Medicine: published August 30, 2016 | https://doi.org/10.1371/journal.pmed.1002117
Essay
Make Data Sharing Routine to Prepare for Public Health Emergencies
PLOS Medicine: published August 16, 2016 | https://doi.org/10.1371/journal.pmed.1002109
Perspectives
On Risk Estimation versus Risk Stratification in Early Prostate Cancer
PLOS Medicine: published August 2, 2016 | https://doi.org/10.1371/journal.pmed.1002100
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Progress and Challenges in Scaling Up Laboratory Monitoring of HIV Treatment
PLOS Medicine: published August 23, 2016 | https://doi.org/10.1371/journal.pmed.1002089
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Concussions and Repercussions
PLOS Medicine: published August 23, 2016 | https://doi.org/10.1371/journal.pmed.1002104
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Health in Action
Multidrug-Resistant Tuberculosis Treatment in North Korea: Is Scale-Up Possible?
PLOS Medicine: published August 2, 2016 | https://doi.org/10.1371/journal.pmed.1002062
Policy Forums
Transitioning to Country Ownership of HIV Programs in Rwanda
PLOS Medicine: published August 9, 2016 | https://doi.org/10.1371/journal.pmed.1002075
Accelerating the Uptake and Timing of Antiretroviral Therapy Initiation in Sub-Saharan Africa: An Operations Research Agenda
PLOS Medicine: published August 9, 2016 | https://doi.org/10.1371/journal.pmed.1002106
Building from the HIV Response toward Universal Health Coverage
PLOS Medicine: published August 16, 2016 | https://doi.org/10.1371/journal.pmed.1002083
Guidelines and Guidance
Core Outcomes for Colorectal Cancer Surgery: A Consensus Study
PLOS Medicine: published August 9, 2016 | https://doi.org/10.1371/journal.pmed.1002071
Research Articles
South Asia as a Reservoir for the Global Spread of Ciprofloxacin-Resistant Shigella sonnei: A Cross-Sectional Study
PLOS Medicine: published August 2, 2016 | https://doi.org/10.1371/journal.pmed.1002055
Adverse Renal, Endocrine, Hepatic, and Metabolic Events during Maintenance Mood Stabilizer Treatment for Bipolar Disorder: A Population-Based Cohort Study
PLOS Medicine: published August 2, 2016 | https://doi.org/10.1371/journal.pmed.1002058
Improving Clinical Risk Stratification at Diagnosis in Primary Prostate Cancer: A Prognostic Modelling Study
PLOS Medicine: published August 2, 2016 | https://doi.org/10.1371/journal.pmed.1002063
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Facility-Based Delivery during the Ebola Virus Disease Epidemic in Rural Liberia: Analysis from a Cross-Sectional, Population-Based Household Survey
PLOS Medicine: published August 2, 2016 | https://doi.org/10.1371/journal.pmed.1002096
Adjuvant Trastuzumab in HER2-Positive Early Breast Cancer by Age and Hormone Receptor Status: A Cost-Utility Analysis
PLOS Medicine: published August 9, 2016 | https://doi.org/10.1371/journal.pmed.1002067
Glycemic Control and the Risk of Tuberculosis: A Cohort Study
PLOS Medicine: published August 9, 2016 | https://doi.org/10.1371/journal.pmed.1002072
Associations between Mental Health and Ebola-Related Health Behaviors: A Regionally Representative Cross-sectional Survey in Post-conflict Sierra Leone
PLOS Medicine: published August 9, 2016 | https://doi.org/10.1371/journal.pmed.1002073
Uptake of Home-Based HIV Testing, Linkage to Care, and Community Attitudes about ART in Rural KwaZulu-Natal, South Africa: Descriptive Results from the First Phase of the ANRS 12249 TasP Cluster-Randomised Trial
PLOS Medicine: published August 9, 2016 | https://doi.org/10.1371/journal.pmed.1002107
Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model Analysis
PLOS Medicine: published August 16, 2016 | https://doi.org/10.1371/journal.pmed.1002090
Assessment of Adverse Events in Protocols, Clinical Study Reports, and Published Papers of Trials of Orlistat: A Document Analysis
PLOS Medicine: published August 16, 2016 | https://doi.org/10.1371/journal.pmed.1002101
Measuring Burden of Unhealthy Behaviours Using a Multivariable Predictive Approach: Life Expectancy Lost in Canada Attributable to Smoking, Alcohol, Physical Inactivity, and Diet
PLOS Medicine: published August 16, 2016 | https://doi.org/10.1371/journal.pmed.1002082
Duration of Adulthood Overweight, Obesity, and Cancer Risk in the Women’s Health Initiative: A Longitudinal Study from the United States
PLOS Medicine: published August 16, 2016 | https://doi.org/10.1371/journal.pmed.1002081
Availability and Use of HIV Monitoring and Early Infant Diagnosis Technologies in WHO Member States in 2011–2013: Analysis of Annual Surveys at the Facility Level
PLOS Medicine: published August 23, 2016 | https://doi.org/10.1371/journal.pmed.1002088
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Integrated Delivery of Antiretroviral Treatment and Pre-exposure Prophylaxis to HIV-1–Serodiscordant Couples: A Prospective Implementation Study in Kenya and Uganda
PLOS Medicine: published August 23, 2016 | https://doi.org/10.1371/journal.pmed.1002099
Long-Term Outcomes Associated with Traumatic Brain Injury in Childhood and Adolescence: A Nationwide Swedish Cohort Study of a Wide Range of Medical and Social Outcomes
PLOS Medicine: published August 23, 2016 | https://doi.org/10.1371/journal.pmed.1002103
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Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent
PLOS Medicine: published August 23, 2016 | https://doi.org/10.1371/journal.pmed.1002105
Pancreatic Cancer Surgical Resection Margins: Molecular Assessment by Mass Spectrometry Imaging
PLOS Medicine: published August 30, 2016 | https://doi.org/10.1371/journal.pmed.1002108
Comparison of Outcomes before and after Ohio's Law Mandating Use of the FDA-Approved Protocol for Medication Abortion: A Retrospective Cohort Study
PLOS Medicine: published August 30, 2016 | https://doi.org/10.1371/journal.pmed.1002110
Social Dancing and Incidence of Falls in Older Adults: A Cluster Randomised Controlled Trial
PLOS Medicine: published August 30, 2016 | https://doi.org/10.1371/journal.pmed.1002112