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Correction: Impact of Replacing Smear Microscopy with Xpert MTB/RIF for Diagnosing Tuberculosis in Brazil: A Stepped-Wedge Cluster-Randomized Trial

  • Betina Durovni,
  • Valeria Saraceni,
  • Susan van den Hof,
  • Anete Trajman,
  • Marcelo Cordeiro-Santos,
  • Solange Cavalcante,
  • Alexandre Menezes,
  • Frank Cobelens

Correction: Impact of Replacing Smear Microscopy with Xpert MTB/RIF for Diagnosing Tuberculosis in Brazil: A Stepped-Wedge Cluster-Randomized Trial

  • Betina Durovni, 
  • Valeria Saraceni, 
  • Susan van den Hof, 
  • Anete Trajman, 
  • Marcelo Cordeiro-Santos, 
  • Solange Cavalcante, 
  • Alexandre Menezes, 
  • Frank Cobelens
PLOS
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During a secondary analysis, the authors discovered 147 duplicate entries in their study database that consists of over 30,000 entries. The duplication of entries was randomly distributed and after reanalysis only minor changes in effect measures, which do not impact the authors’ conclusions, were observed. For example, the notification rate ratio for laboratory confirmed TB (the study’s primary endpoint) was 1.59 (95% CI 1.31–1.88) in the original analysis and 1.60 (95% CI 1.31–1.89) in the revised analysis. A revised version of Table 4 is presented below.

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Table 4. Cluster-averaged notification rates, differences and ratios for lab-confirmed TB, TB with negative test result, TB with no testing, and overall pulmonary TB.

http://dx.doi.org/10.1371/journal.pmed.1001928.t001

Reference

  1. 1. Durovni B, Saraceni V, van den Hof S, Trajman A, Cordeiro-Santos M, Cavalcante S, et al. (2014) Impact of Replacing Smear Microscopy with Xpert MTB/RIF for Diagnosing Tuberculosis in Brazil: A Stepped-Wedge Cluster-Randomized Trial. PLoS Med 11(12): e1001766. doi: 10.1371/journal.pmed.1001766. pmid:25490549