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Open Access
Peer-reviewed
Research Article
Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis
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Richard M. Hoglund,
Affiliations WorldWide Antimalarial Resistance Network, Oxford, United Kingdom, Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Lesley Workman,
Affiliations WorldWide Antimalarial Resistance Network, Oxford, United Kingdom, Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa
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Michael D. Edstein,
Affiliation Department of Drug Evaluation, Australian Army Malaria Institute, Brisbane, Queensland, Australia
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Nguyen Xuan Thanh,
Affiliation Department of Malaria, Military Institute of Hygiene and Epidemiology, Hanoi, Viet Nam
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Nguyen Ngoc Quang,
Affiliation Department of Infectious Diseases, Military Hospital 108, Hanoi, Viet Nam
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Issaka Zongo,
Affiliations Institut de Recherche en Sciences de la Santé, Direction Régionale de l’Ouest, Bobo-Dioulasso, Burkina Faso, London School of Hygiene & Tropical Medicine, London, United Kingdom
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Jean Bosco Ouedraogo,
Affiliation Institut de Recherche en Sciences de la Santé, Direction Régionale de l’Ouest, Bobo-Dioulasso, Burkina Faso
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Steffen Borrmann,
Affiliations Kenya Medical Research Institute–Wellcome Trust Research Programme, Kilifi, Kenya, Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany
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Leah Mwai,
Affiliations Kenya Medical Research Institute–Wellcome Trust Research Programme, Kilifi, Kenya, Joanna Briggs Affiliate Centre for Evidence-Based Health Care, Evidence Synthesis and Translation Unit, Afya Research Africa, Nairobi, Kenya
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Christian Nsanzabana,
Affiliations WorldWide Antimalarial Resistance Network, Oxford, United Kingdom, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Ric N. Price,
Affiliations WorldWide Antimalarial Resistance Network, Oxford, United Kingdom, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia
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Prabin Dahal,
Affiliations WorldWide Antimalarial Resistance Network, Oxford, United Kingdom, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Nancy C. Sambol,
Affiliation Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America
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Sunil Parikh,
Affiliation Yale School of Public Health and Medicine, New Haven, Connecticut, United States of America
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Francois Nosten,
Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Shoklo Malaria Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand
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Elizabeth A. Ashley,
Affiliation Shoklo Malaria Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand
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Aung Pyae Phyo,
Affiliation Shoklo Malaria Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand
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Khin Maung Lwin,
Affiliation Shoklo Malaria Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand
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Rose McGready,
Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Shoklo Malaria Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand
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Nicholas P. J. Day,
Affiliations Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Philippe J. Guerin,
Affiliations WorldWide Antimalarial Resistance Network, Oxford, United Kingdom, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Nicholas J. White,
Affiliations Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Karen I. Barnes,
Affiliations WorldWide Antimalarial Resistance Network, Oxford, United Kingdom, Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa
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Joel Tarning
* E-mail: joel@tropmedres.ac
Affiliations WorldWide Antimalarial Resistance Network, Oxford, United Kingdom, Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis
- Richard M. Hoglund,
- Lesley Workman,
- Michael D. Edstein,
- Nguyen Xuan Thanh,
- Nguyen Ngoc Quang,
- Issaka Zongo,
- Jean Bosco Ouedraogo,
- Steffen Borrmann,
- Leah Mwai,
- Christian Nsanzabana
- Published: January 10, 2017
- https://doi.org/10.1371/journal.pmed.1002212