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Open Access
Peer-reviewed
Research Article
A Genome-Wide Screen for Promoter Methylation in Lung Cancer Identifies Novel Methylation Markers for Multiple Malignancies
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David S Shames,
Affiliations Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Department of Pharmacology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
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Luc Girard,
Affiliations Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Department of Pharmacology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
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Boning Gao,
Affiliations Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Department of Pharmacology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
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Mitsuo Sato,
Affiliations Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
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Cheryl M Lewis,
Affiliation Department of Surgery, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
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Narayan Shivapurkar,
Affiliations Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Department of Pathology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
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Aixiang Jiang,
Affiliation Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
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Charles M Perou,
Affiliations Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America , Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Young H Kim,
Affiliation Department of Pathology, Stanford University, Stanford, California, United States of America
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Jonathan R Pollack,
Affiliation Department of Pathology, Stanford University, Stanford, California, United States of America
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Kwun M Fong,
Affiliation Department of Thoracic Medicine, The Prince Charles Hospital, University of Queensland, Brisbane, Australia
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Chi-Leung Lam,
Affiliation University Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China
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Maria Wong,
Affiliation University Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China
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Yu Shyr,
Affiliation Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
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Rita Nanda,
Affiliation Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America
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Olufunmilayo I Olopade,
Affiliation Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America
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William Gerald,
Affiliation Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
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David M Euhus,
Affiliation Department of Surgery, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
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Jerry W Shay,
Affiliations Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Department of Cell Biology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
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Adi F Gazdar,
Affiliations Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Department of Pathology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
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John D Minna
*To whom correspondence should be addressed. E-mail: John.Minna@UTsouthwestern.edu
Affiliations Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Department of Pharmacology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America , Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
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A Genome-Wide Screen for Promoter Methylation in Lung Cancer Identifies Novel Methylation Markers for Multiple Malignancies
- David S Shames,
- Luc Girard,
- Boning Gao,
- Mitsuo Sato,
- Cheryl M Lewis,
- Narayan Shivapurkar,
- Aixiang Jiang,
- Charles M Perou,
- Young H Kim,
- Jonathan R Pollack
- Published: December 26, 2006
- https://doi.org/10.1371/journal.pmed.0030486