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N348I in the Connection Domain of HIV-1 Reverse Transcriptase Confers Zidovudine and Nevirapine Resistance

  • Soo-Huey Yap,

    Affiliations Molecular Interactions Group, Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia , School of Applied Sciences and Engineering, Monash University, Churchill, Victoria, Australia

  • Chih-Wei Sheen,

    Affiliation Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

  • Jonathan Fahey,

    Affiliations Molecular Interactions Group, Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia , Department of Microbiology, Monash University, Clayton, Victoria, Australia

  • Mark Zanin,

    Affiliation Molecular Interactions Group, Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia

  • David Tyssen,

    Affiliation Molecular Interactions Group, Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia

  • Viviane Dias Lima,

    Affiliation British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada

  • Brian Wynhoven,

    Affiliation British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada

  • Michael Kuiper,

    Affiliation Victorian Partnership for Advanced Computing, Carlton South, Victoria, Australia

  • Nicolas Sluis-Cremer,

    Affiliation Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

  • P. Richard Harrigan,

    Affiliation British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada

  • Gilda Tachedjian

    To whom correspondence should be addressed. E-mail: gildat@burnet.edu.au

    Affiliations Molecular Interactions Group, Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia , Department of Microbiology, Monash University, Clayton, Victoria, Australia , Department of Medicine, Monash University, Melbourne, Victoria, Australia

N348I in the Connection Domain of HIV-1 Reverse Transcriptase Confers Zidovudine and Nevirapine Resistance

  • Soo-Huey Yap, 
  • Chih-Wei Sheen, 
  • Jonathan Fahey, 
  • Mark Zanin, 
  • David Tyssen, 
  • Viviane Dias Lima, 
  • Brian Wynhoven, 
  • Michael Kuiper, 
  • Nicolas Sluis-Cremer, 
  • P. Richard Harrigan
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