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Figure 1.

Quality of individual study reports (n = 17 items, n = 83 studies), based on the REMARK guidelines [11].

Definitions of each item are given in Table S2.

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Figure 2.

Forest plot of the effect of CRP on prognosis among patients with stable coronary disease.

Studies are grouped according to the extent of adjustment for conventional risk factors.

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Figure 3.

Funnel plot with contours showing different levels of study significance.

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Figure 4.

Meta-regression of categorical and continuous study level covariates.

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Figure 5.

Detection rates at 10% false positive rate and c-statistic for individual studies, and pooled ROC curve.

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