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Decreased Brain Volume in Adults with Childhood Lead Exposure

Figure 5

Sex Influences Brain Volume Loss Associated with Lead Exposure (Females)

A composite representation of regions with significant volume loss for CLS participants associated with mean childhood blood lead concentrations is shown in red and yellow overlaid upon a standard brain template for females (n = 74). The model is adjusted for age at time of scanning and birth weight, using a cluster threshold of 700 voxels and unadjusted p ≤ 0.001. Views are the same as shown in Figure 1; brain template source reference [51].

Figure 5

doi: https://doi.org/10.1371/journal.pmed.0050112.g005