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Posted by plosmedicine on 30 Mar 2009 at 23:45 GMT

Author: Carolyn Rees
Position: M.D
Institution: No affiliation was given
Submitted Date: August 27, 2005
Published Date: September 1, 2005
This comment was originally posted as a “Reader Response” on the publication date indicated above. All Reader Responses are now available as comments.

Thank you, thank you, thank you, PLoS! Hello to Dr Varmus from one of your old students from UCSF class of 1979. My practice of internal medicine offers me daily opportunities to observe fascinating phenomena that I would love to research further but am frustrated by the narrow range of material in the internal medicine publications and the difficulty in searching outside the areas with which I am most familiar. I am sick to death of endless drug trials showing infinitesimal improvements on long term outcomes with one cardiovascular drug after another. The information my patients demand, "what harm will I suffer if I don't take the recommended pill, or if I don't get mammograms, or if I don't get my prostate checked?" is not available. I receive mailings from pharmacy benefit companies (value-added service to the insurance plan) urging me to prescribe ACE inhibitors and statins to patients for whom I have prescribed metformin or diabetic medication. My patients, sensible Idaho medicare users, say the pills are expensive and make them feel bad. THIS IS RIDICULOUS. I am looking forward to reading some ORIGINAL research, not just regurgitated material churned out to satisfy fellowship requirements. Thank for your patience reading this.

No competing interests declared.