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Why stem cells turn cancerous

Posted by plosmedicine on 31 Mar 2009 at 00:34 GMT

Author: Angel Jimenez
Position: unemployed
Institution: home
Submitted Date: February 21, 2009
Published Date: February 24, 2009
This comment was originally posted as a “Reader Response” on the publication date indicated above. All Reader Responses are now available as comments.

These results point clearly to cells that are seeking their true place in a new multicellular environment. Unable to make contact with their own kind, they begin to express earlier Cell Recognition Factors. Tied in with the expression of these early-development factors comes the cancerous state which reflects the behavior of multicellular cells early in their development. Please see http://ortholex.blogspot.... for more details.

If you take any stem cell and put it in a place it doesn't recognize, it will become cancerous. This is particularly so with allografts. Of course, the immune system or a self-destruct mechanism may intervene.

Angel Jimenez, B.A. (Biology '73)

No competing interests declared.