About the Authors

Kunal N. Karmali

Roles Conceptualization, Investigation, Methodology, Writing – review & editing

Affiliation Department of Medicine, Northwestern University, Chicago, Illinois, United States of America

Donald M. Lloyd-Jones

Roles Investigation, Methodology, Writing – review & editing

Affiliation Department of Medicine, Northwestern University, Chicago, Illinois, United States of America

Joep van der Leeuw

Roles Investigation, Methodology, Writing – review & editing

Affiliation University Medical Center Utrecht, Department of Vascular Medicine, Utrecht, Netherlands

David C. Goff Jr.

Roles Investigation, Methodology, Writing – review & editing

Affiliation National Heart, Lung, and Blood Institute, Division of Cardiovascular Sciences, Bethesda, Maryland, United States of America

Salim Yusuf

Roles Investigation, Methodology, Writing – review & editing

Affiliation Population Health Research Institute, McMaster University, Hamilton, Canada

Alberto Zanchetti

Roles Investigation, Methodology, Writing – review & editing

Affiliation The Istituto Auxologico Italiano, Milan, Italy

Paul Glasziou

Roles Investigation, Methodology, Writing – review & editing

Affiliation Centre for Research in Evidence Based Practice, Bond University, Robina, Australia

Rodney Jackson

Roles Investigation, Methodology, Writing – review & editing

Affiliation School of Population Health, Faculty of Medical and Health Science, University of Auckland, Auckland, New Zealand

Mark Woodward

Roles Investigation, Methodology, Writing – review & editing

Affiliations The George Institute for Global Health, University of Oxford, Oxford, United Kingdom, The George Institute for Global Health, Sydney, Australia

Anthony Rodgers

Roles Investigation, Methodology, Writing – review & editing

Affiliation The George Institute for Global Health, Sydney, Australia

Bruce C. Neal

Roles Investigation, Methodology, Writing – review & editing

Affiliation The George Institute for Global Health, Sydney, Australia

Eivind Berge

Roles Investigation, Methodology, Writing – review & editing

Affiliation Department of Cardiology, Oslo University Hospital, Oslo, Norway

Koon Teo

Roles Data curation, Methodology, Writing – review & editing

Affiliation Population Health Research Institute, McMaster University, Hamilton, Canada

Barry R. Davis

Roles Data curation, Methodology, Writing – review & editing

Affiliation School of Public Health, University of Texas, Dallas, Texas, United States of America

John Chalmers

Roles Data curation, Methodology, Writing – review & editing

Affiliation The George Institute for Global Health, Sydney, Australia

Carl Pepine

Roles Data curation, Methodology, Writing – review & editing

Affiliation Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida, United States of America

Kazem Rahimi

Roles Project administration, Writing – review & editing

kazem.rahimi@georgeinstitute.ox.ac.uk

Affiliation The George Institute for Global Health, University of Oxford, Oxford, United Kingdom

Johan Sundström

Roles Conceptualization, Data curation, Investigation, Methodology, Visualization, Writing – review & editing

Affiliation Department of Medical Sciences, Uppsala University, and Uppsala Clinical Research Center, Uppsala, Sweden

on behalf of the Blood Pressure Lowering Treatment Trialists’ Collaboration

Membership of the Blood Pressure Lowering Treatment Trialists’ Collaboration is provided in the Acknowledgments.

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: KR receives a stipend as a specialty consulting editor for PLOS Medicine and serves on the journal's editorial board. KR served as Guest Editor on PLOS Medicine’s Special Issue on Cardiovascular Disease and Multimorbidity. MW is a consultant to Amgen on analyses of US health data. George Health Enterprises, the social enterprise arm of The George Institute for Global Health, has received investment to develop fixed-dose combination products containing aspirin, statin and blood pressure lowering drugs. George Health Enterprises has submitted patents for low-dose blood pressure combinations, on which AR is listed as one of the inventors. AR does not have a financial interest in these planned products. JC has received research grants, administered through the University of Sydney, as Principal Investigator for the ADVANCE trial and ADVANCE-ON post trial study, from the National Health and Medical Research Council of Australia and from Servier and JC has also received personal fees from Servier for speaking about these studies at scientific meetings.