About the Authors
- Jake Dunning
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Contributed equally to this work with: Jake Dunning, Foday Sahr
Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- Foday Sahr
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Contributed equally to this work with: Jake Dunning, Foday Sahr
Affiliations Military 34 Hospital, Republic of Sierra Leone Armed Forces, Freetown, Sierra Leone, College of Medicine and Allied Health Sciences, Freetown, Sierra Leone
- Amanda Rojek
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Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- Fiona Gannon
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Affiliation GOAL Global, Dun Laoghaire, Ireland
- Gail Carson
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Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, International Severe Acute Respiratory and Emerging Infection Consortium Coordinating Centre, University of Oxford, Oxford, United Kingdom
- Baimba Idriss
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Affiliation Military 34 Hospital, Republic of Sierra Leone Armed Forces, Freetown, Sierra Leone
- Thomas Massaquoi
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Affiliation Military 34 Hospital, Republic of Sierra Leone Armed Forces, Freetown, Sierra Leone
- Regina Gandi
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Affiliation Military 34 Hospital, Republic of Sierra Leone Armed Forces, Freetown, Sierra Leone
- Sebatu Joseph
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Affiliation Military 34 Hospital, Republic of Sierra Leone Armed Forces, Freetown, Sierra Leone
- Hassan K. Osman
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Affiliation Military 34 Hospital, Republic of Sierra Leone Armed Forces, Freetown, Sierra Leone
- Timothy J. G. Brooks
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Affiliation Rare and Imported Pathogens Laboratory, Public Health England, Porton Down, United Kingdom
- Andrew J. H. Simpson
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Affiliation Rare and Imported Pathogens Laboratory, Public Health England, Porton Down, United Kingdom
- Ian Goodfellow
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Affiliation Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
- Lucy Thorne
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Affiliation Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
- Armando Arias
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Affiliation Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
- Laura Merson
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Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- Lyndsey Castle
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Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- Rebecca Howell-Jones
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Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- Raul Pardinaz-Solis
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Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- Benjamin Hope-Gill
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Affiliation Cardiff and Vale University Health Board, Cardiff, Wales, United Kingdom
- Mauricio Ferri
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Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- Jennifer Grove
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Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- Mark Kowalski
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Affiliation Tekmira Pharmaceuticals, Burnaby, British Columbia, Canada
- Kasia Stepniewska
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Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- Trudie Lang
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Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- John Whitehead
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Affiliation Department of Mathematics and Statistics, Lancaster University, Lancaster, United Kingdom
- Piero Olliaro
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Affiliations Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom, UNICEF–UNDP–World Bank–WHO Special Programme for Research and Training in Tropical Diseases, Geneva, Switzerland
- Mohammed Samai
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Affiliation College of Medicine and Allied Health Sciences, Freetown, Sierra Leone
- Peter W. Horby
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* E-mail: peter.horby@ndm.ox.ac.uk
Affiliation Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom
- for the RAPIDE-TKM trial team
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¶Membership of the RAPIDE-TKM trial team is provided in the Acknowledgments.
Competing Interests
We have read the journal's policy and the authors of this manuscript have the following competing interests: MK is an employee of Arbutus Biopharma (previously known as Tekmira Pharmaceuticals).
Author Contributions
Conceived and designed the experiments: PWH TL PO JW. Performed the experiments: JD FS AR FG GC BI TM RG SJ HKO TJGB AJHS IG LT AA LM LC RH-J RP-S BH-G MF JG MK KS TL JW PO MS PWH. Analyzed the data: KS JW PWH JD. Contributed reagents/materials/analysis tools: TJGB AJHS LT AA IG. Wrote the first draft of the manuscript: PWH JD FS PO. Contributed to the writing of the manuscript: TL FS GC AR FG IG JW KS. Enrolled patients: JD AR BI TM RG SJ. Agree with the manuscript’s results and conclusions: JD FS AR FG GC BI TM RG SJ HKO TJGB AJHS IG LT AA LM LC RH-J RP-S BH-G MF JG MK KS TL JW PO MS PWH. All authors have read, and confirm that they meet, ICMJE criteria for authorship.