About the Authors
- Peter G. Kremsner
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* E-mail: peter.kremsner@uni-tuebingen.de (PGK); s.krishna@sgul.ac.uk (SK)
Affiliations Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany, Centre de Recherches Médicales de Lambaréné, Hôpital Albert Schweitzer, Lambaréné, Gabon
- Akim A. Adegnika
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Affiliations Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany, Centre de Recherches Médicales de Lambaréné, Hôpital Albert Schweitzer, Lambaréné, Gabon
- Aurore B. Hounkpatin
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Affiliations Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany, Centre de Recherches Médicales de Lambaréné, Hôpital Albert Schweitzer, Lambaréné, Gabon
- Jeannot F. Zinsou
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Affiliations Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany, Centre de Recherches Médicales de Lambaréné, Hôpital Albert Schweitzer, Lambaréné, Gabon
- Terrie E. Taylor
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Affiliation Blantyre Malaria Project, University of Malawi College of Medicine, Blantyre, Malawi
- Yamikani Chimalizeni
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Affiliation Blantyre Malaria Project, University of Malawi College of Medicine, Blantyre, Malawi
- Alice Liomba
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Affiliation Blantyre Malaria Project, University of Malawi College of Medicine, Blantyre, Malawi
- Maryvonne Kombila
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Affiliation Department of Parasitology Mycology, Faculty of Medicine, Université des Sciences de la Santé, Libreville, Gabon
- Marielle K. Bouyou-Akotet
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Affiliation Department of Parasitology Mycology, Faculty of Medicine, Université des Sciences de la Santé, Libreville, Gabon
- Denise P. Mawili Mboumba
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Affiliation Department of Parasitology Mycology, Faculty of Medicine, Université des Sciences de la Santé, Libreville, Gabon
- Tsiri Agbenyega
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Affiliations Department of Physiology, University of Science and Technology, School of Medical Sciences, Kumasi, Ghana, Departments of Child Health and Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana
- Daniel Ansong
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Affiliations Department of Physiology, University of Science and Technology, School of Medical Sciences, Kumasi, Ghana, Departments of Child Health and Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana
- Justice Sylverken
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Affiliations Department of Physiology, University of Science and Technology, School of Medical Sciences, Kumasi, Ghana, Departments of Child Health and Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana
- Bernhards R. Ogutu
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Affiliation Centre for Clinical Research, Kenya Medical Research Institute, Kisumu, Kenya
- Godfrey A. Otieno
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Affiliation Centre for Clinical Research, Kenya Medical Research Institute, Kisumu, Kenya
- Anne Wangwe
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Affiliation Centre for Clinical Research, Kenya Medical Research Institute, Kisumu, Kenya
- Kalifa A. Bojang
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Affiliation Medical Research Council Laboratories, Fajara, The Gambia
- Uduak Okomo
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Affiliation Medical Research Council Laboratories, Fajara, The Gambia
- Frank Sanya-Isijola
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Affiliation Medical Research Council Laboratories, Fajara, The Gambia
- Charles R. Newton
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Affiliation Centre for Geographic Medicine Research–Coast, Kenya Medical Research Institute, Kilifi, Kenya
- Patricia Njuguna
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Affiliation Centre for Geographic Medicine Research–Coast, Kenya Medical Research Institute, Kilifi, Kenya
- Michael Kazungu
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Affiliation Centre for Geographic Medicine Research–Coast, Kenya Medical Research Institute, Kilifi, Kenya
- Reinhold Kerb
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Affiliations Dr. Margarete Fischer-Bosch-Institut für Klinische Pharmakologie, Stuttgart, Germany, Eberhard Karls Universität Tübingen, Tübingen, Germany
- Mirjam Geditz
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Affiliations Dr. Margarete Fischer-Bosch-Institut für Klinische Pharmakologie, Stuttgart, Germany, Eberhard Karls Universität Tübingen, Tübingen, Germany
- Matthias Schwab
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Affiliations Dr. Margarete Fischer-Bosch-Institut für Klinische Pharmakologie, Stuttgart, Germany, Abteilung Klinische Pharmakologie, Universitätsklinikum Tübingen, Tübingen, Germany
- Thirumalaisamy P. Velavan
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Affiliation Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany
- Christian Nguetse
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Affiliation Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany
- Carsten Köhler
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Affiliation Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany
- Saadou Issifou
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Affiliations Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany, Centre de Recherches Médicales de Lambaréné, Hôpital Albert Schweitzer, Lambaréné, Gabon
- Stefanie Bolte
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Affiliation Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany
- Thomas Engleitner
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Affiliation Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany
- Benjamin Mordmüller
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Affiliations Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany, Centre de Recherches Médicales de Lambaréné, Hôpital Albert Schweitzer, Lambaréné, Gabon
- Sanjeev Krishna
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* E-mail: peter.kremsner@uni-tuebingen.de (PGK); s.krishna@sgul.ac.uk (SK)
Affiliations Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany, Centre de Recherches Médicales de Lambaréné, Hôpital Albert Schweitzer, Lambaréné, Gabon, Institute for Infection and Immunity, St George’s, University of London, London, United Kingdom
Competing Interests
GK, BM, CK, SB, and TE report grants from European and Developing Countries Clinical Trials Partnership and Bundesministerium für Building und Forschung Deutschland for the conduct of the study. SK reports grants from European and Developing Countries Clinical Trials Partnership for the conduct of the study, personal fees from Merck Serono and shareholder at QuantuMDx. AAA, JFZ, ABH, TET, YC, AL, MK, MKBA, DPMM, TA, DA, JS, BRO, GAO, AW, KAB, UO, FSI, CRN, PN, MK, and SI report grant from European and Developing Countries Clinical Trials Partnership for the conduct of the study. MS, MG, and RK report grants from DFG and Robert Bosch Stiftung for the conduct of the study. TPV and CN report grant from Deutsche Forschungsgemieinschaft for the conduct of the study. SK is a member of the Editorial Board of PLOS Medicine.
Author Contributions
Conceived and designed the experiments: PGK SK. Performed the experiments: AAA JFZ ABH TET YC AL MK MKBA DPMM TA DA JS BRO GAO AW KAB UO FSI CRN PN MK SI TPV CN MS MG RK. Analyzed the data: PGK SK BM TE MS MG RK TPV CN. Wrote the first draft of the manuscript: SK PGK BM. Contributed to the writing of the manuscript: AAA JFZ ABH TET YC AL MK MKBA DPMM TA DA JS BRO GAO AW KAB UO FSI CRN PN MK SI. Enrolled patients: AAA JFZ ABH TET YC AL MK MKBA DPMM TA DA JS BRO GAO AW KAB UO FSI CRN PN MK SI. Agree with the manuscript’s results and conclusions: AAA JFZ ABH TET YC AL MK MKBA DPMM TA DA JS BRO GAO AW KAB UO FSI CRN PN MK SI PGK SK BM MS MG RK TPV CN CK SB TE. Overall project managers: CK SB. All authors have read, and confirm that they meet, ICMJE criteria for authorship.