About the Authors

Wei-Li Xu

weili.xu@ki.se

Affiliations Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden, Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China

Nancy L. Pedersen

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Lina Keller

Affiliations Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden, Alzheimer’s Disease Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden

Grégoria Kalpouzos

Affiliation Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden

Hui-Xin Wang

Affiliation Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden

Caroline Graff

Affiliations Alzheimer’s Disease Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden, Department of Geriatric Medicine, Karolinska University Hospital, Stockholm, Sweden

Bengt Winblad

Affiliations Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden, Alzheimer’s Disease Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden

Lars Bäckman

Affiliation Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden

Laura Fratiglioni

Affiliations Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden, Stockholm Gerontology Research Center, Stockholm, Sweden

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WLX LF. Performed the experiments: WLX. Analyzed the data: WLX NLP LK GK HW CG BW LB LF. Contributed to the writing of the manuscript: WLX NLP LK GK HW CG BW LB LF. Contributed to the acquisition of the initial data: LF LB BW. All authors have read, and confirm that they meet, ICMJE criteria for authorship. Wrote the first draft of the manuscript: WLX. Agree with the manuscript’s results and conclusions: WLX NLP LK GK HW CG BW LB LF.