About the Authors

Fiona M. Blows

Contributed equally to this work with: Fiona M. Blows, Kristy E. Driver

Affiliation Department of Oncology, University of Cambridge, United Kingdom

Kristy E. Driver

Contributed equally to this work with: Fiona M. Blows, Kristy E. Driver

Affiliation Department of Oncology, University of Cambridge, United Kingdom

Marjanka K. Schmidt

Affiliation Netherlands Cancer Institute, Amsterdam, The Netherlands

Annegien Broeks

Affiliation Netherlands Cancer Institute, Amsterdam, The Netherlands

Flora E. van Leeuwen

Affiliation Netherlands Cancer Institute, Amsterdam, The Netherlands

Jelle Wesseling

Affiliation Netherlands Cancer Institute, Amsterdam, The Netherlands

Maggie C. Cheang

Affiliation Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, Canada

Karen Gelmon

Affiliation Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, Canada

Torsten O. Nielsen

Affiliation Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, Canada

Carl Blomqvist

Affiliation Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland

Päivi Heikkilä

Affiliation Department of Pathology, Helsinki University Central Hospital, Helsinki, Finland

Tuomas Heikkinen

Affiliation Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland

Heli Nevanlinna

Affiliation Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland

Lars A. Akslen

Affiliation The Gade Institute, Section for Pathology, University of Bergen, Haukeland University Hospital, Bergen, Norway

Louis R. Bégin

Affiliation Department of Pathology, McGill University and Hôpital du Sacré-Coeur de Montréal, Montreal, Quebec, Canada

William D. Foulkes

Affiliation Program in Cancer Genetics, Departments of Oncology and Human Genetics, McGill University, Montreal, Quebec, Canada

Fergus J. Couch

Affiliation Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

Xianshu Wang

Affiliation Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

Vicky Cafourek

Affiliation Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America

Janet E. Olson

Affiliation Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America

Laura Baglietto

Affiliation Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia

Graham G. Giles

Affiliation Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia

Gianluca Severi

Affiliation Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia

Catriona A. McLean

Affiliation The Alfred Hospital, Melbourne, Australia

Melissa C. Southey

Affiliation Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Australia

Emad Rakha

Affiliation Departments of Histopathology and Surgery, The Breast Unit, Nottingham City Hospital NHS Trust and University of Nottingham, Nottingham, United Kingdom

Andrew R. Green

Affiliation Departments of Histopathology and Surgery, The Breast Unit, Nottingham City Hospital NHS Trust and University of Nottingham, Nottingham, United Kingdom

Ian O. Ellis

Affiliation Departments of Histopathology and Surgery, The Breast Unit, Nottingham City Hospital NHS Trust and University of Nottingham, Nottingham, United Kingdom

Mark E. Sherman

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America

Jolanta Lissowska

Affiliation M. Sklodowska-Curie Memorial Cancer Center & Institute of Oncology, Warsaw, Poland

William F. Anderson

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America

Angela Cox

Affiliation Institute for Cancer Studies, University of Sheffield School of Medicine, Sheffield, United Kingdom

Simon S. Cross

Affiliation Academic Unit of Pathology, University of Sheffield School of Medicine, Sheffield, United Kingdom

Malcolm W. R. Reed

Affiliation Academic Unit of Surgical Oncology, University of Sheffield School of Medicine, Sheffield, United Kingdom

Elena Provenzano

Affiliation Department of Oncology, University of Cambridge, United Kingdom

Sarah-Jane Dawson

Affiliation Department of Oncology, University of Cambridge, United Kingdom

Alison M. Dunning

Affiliations Department of Oncology, University of Cambridge, United Kingdom, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Manjeet Humphreys

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Douglas F. Easton

Affiliations Department of Oncology, University of Cambridge, United Kingdom, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Montserrat García-Closas

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America

Carlos Caldas

Affiliation Department of Oncology, University of Cambridge, United Kingdom

Paul D. Pharoah

paul.pharoah@srl.cam.ac.uk

Affiliations Department of Oncology, University of Cambridge, United Kingdom, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

David Huntsman

Affiliation Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, Canada

Competing Interests

Research in the Genetic Pathology Evaluation Centre is supported in part by an unrestricted educational grant from sanofi-aventis Canada.

Author Contributions

ICMJE criteria for authorship read and met: FMB KED MKS AB FEvL JW MCC KG TON CB PH TH HN LA LRB WF FJC XW VC JEO LB GGG GS CAM MCS ER ARG IOE MES JL WA AC SSC MWRR EP SJD AMD MKH DFE MGC CC PDP DH. Agree with the manuscript's results and conclusions: FMB KED MKS AB FEvL JW MCC KG TON CB PH TH HN LA LRB WF FJC XW VC JEO LB GGG GS CAM MCS ER ARG IOE MES JL WA AC SSC MWRR EP SJD AMD MKH DFE MGC CC PDP DH. Designed the experiments/the study: TON PH MCS IOE JL AMD MGC CC PDP DH. Analyzed the data: FMB KED PH LRB XW MCS MES WA CC PDP. Collected data/did experiments for the study: FMB KED MKS AB JW MCC TON CB PH TH HN LA LRB WF FJC XW VC LB GGG GS CAM MCS ER ARG MES JL AC SSC EP SJD MKH DFE MGC CC PDP DH. Enrolled patients: FEvL KG FJC JEO LB GGG MCS IOE JL MWRR DFE MGC PDP DH. Wrote the first draft of the paper: FMB KED. Contributed to the writing of the paper: MKS FEvL JW KG TON CB PH TH HN LA WF FJC XW JEO LB GGG GS CAM MCS IOE MES JL WA AC SSC MWRR EP SJD DFE MGC CC PDP. Co-ordinated data collation: FMB KED. Contributed to database building and checking of data: MKS. Enrolled patients are derived from a cohort built by me and others: FEvL. Responsible for clinical data integrity: VC. Assistance with TMA construction and scoring of immunohistochemistry: EP. Responsible for pooling data and data cleaning: MH.