About the Authors

Nadeem Sarwar

nadeem.sarwar@phpc.cam.ac.uk

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Thor Aspelund

Affiliations Icelandic Heart Association, Kopavogur, Iceland, University of Iceland, Reykjavik, Iceland

Gudny Eiriksdottir

Affiliations Icelandic Heart Association, Kopavogur, Iceland, University of Iceland, Reykjavik, Iceland

Reeta Gobin

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Sreenivasa Rao Kondapally Seshasai

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Nita G. Forouhi

Affiliation MRC Epidemiology Unit, Cambridge, United Kingdom

Gunnar Sigurdsson

Affiliations Icelandic Heart Association, Kopavogur, Iceland, University of Iceland, Reykjavik, Iceland

John Danesh

Contributed equally to this work with: John Danesh, Vilmundur Gudnason

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Vilmundur Gudnason

Contributed equally to this work with: John Danesh, Vilmundur Gudnason

Affiliations Icelandic Heart Association, Kopavogur, Iceland, University of Iceland, Reykjavik, Iceland

Competing Interests

JD has received research funding from the British Heart Foundation, BUPA Foundation, Denka, diaDexus, European Union, Evelyn Trust, GlaxoSmithKline MRC, Merck, National Heart, Lung, and Blood Institute, National Institute of Neurological Disorders and Stroke, Novartis, Pfizer, Roche, Wellcome Trust and UK Biobank. John Danesh is on the Editorial Board of PLoS Medicine.

Author Contributions

ICMJE criteria for authorship read and met: NS TA GE RG SRKS NGF GS JD VG. Agree with the manuscript's results and conclusions: NS TA GE RG SRKS NGF GS JD VG. Designed the experiments/the study: NS JD VG. Analyzed the data: NS TA. Collected data/did experiments for the study: NS GE RG SRKS GS VG. Enrolled patients: GS. Wrote the first draft of the paper: NS JD. Contributed to the writing of the paper: NS NS TA NGF GS JD VG. Responsible for data from the Reykjavik Study, derived variables, endpoints and analysis: TA. Contributed to critical revisions of the text: RG SRKS JD. Critically interpreted the findings and revised versions of the manuscript: NGF.