About the Authors

Laura Y. Park-Wyllie

parkwylliel@smh.toronto.on.ca

Affiliations Department of Family and Community Medicine, St. Michael's Hospital, Toronto, Ontario, Canada, Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada, Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada

Muhammad M. Mamdani

Affiliations Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada, Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada, Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada

Ping Li

Affiliation Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada

Sudeep S. Gill

Affiliations Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada, Department of Medicine at Queens University, Kingston, Ontario, Canada

Andreas Laupacis

Affiliations Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada, Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada, Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

David N. Juurlink

Affiliations Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada, Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

Competing Interests

MMM was employed at Pfizer Global Pharmaceuticals from January 2006 to April 2007.

Author Contributions

ICMJE criteria for authorship read and met: LPW MMM PL SSG AL DNJ. Agree with the manuscript's results and conclusions: LPW MMM PL SSG AL DNJ. Designed the experiments/the study: LPW MMM SSG AL DNJ. Analyzed the data: LPW PL SSG. Wrote the first draft of the paper: LPW. Contributed to the writing of the paper: LPW MMM PL SSG AL DNJ. Helped to design the study, helped to analyze/interpret the data, and contributed to critical revisions of the manuscript: SSG. Supervised LYPW: DNJ.