About the Authors

Michael Eddleston

eddlestonm@yahoo.com

Affiliations Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom, Ox-Col Collaboration, Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Sri Lanka, South Asian Clinical Toxicology Research Collaboration, Sri Lanka

Peter Eyer

Affiliation Walther Straub Institute of Pharmacology and Toxicology, Ludwig Maximilians University, Munich, Germany

Franz Worek

Affiliation Bundeswehr Institute of Pharmacology and Toxicology, Munich, Germany

Edmund Juszczak

Affiliation Centre for Statistics in Medicine, Wolfson College, University of Oxford, England

Nicola Alder

Affiliation Centre for Statistics in Medicine, Wolfson College, University of Oxford, England

Fahim Mohamed

Affiliations Ox-Col Collaboration, Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Sri Lanka, South Asian Clinical Toxicology Research Collaboration, Sri Lanka

Lalith Senarathna

Affiliations Ox-Col Collaboration, Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Sri Lanka, South Asian Clinical Toxicology Research Collaboration, Sri Lanka

Ariyasena Hittarage

Affiliation Anuradhapura General Hospital, North Central Province, Sri Lanka

Shifa Azher

Affiliation Polonnaruwa General Hospital, North Central Province, Sri Lanka

K. Jeganathan

Affiliation Anuradhapura General Hospital, North Central Province, Sri Lanka

Shaluka Jayamanne

Affiliation Polonnaruwa General Hospital, North Central Province, Sri Lanka

Ludwig von Meyer

Affiliation Institute of Legal Medicine, Ludwig Maximilians University, Munich, Germany

Andrew H. Dawson

Affiliations South Asian Clinical Toxicology Research Collaboration, Sri Lanka, School of Public Health, University of Newcastle, Australia

Mohamed Hussain Rezvi Sheriff

Affiliations Ox-Col Collaboration, Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Sri Lanka, South Asian Clinical Toxicology Research Collaboration, Sri Lanka

Nick A. Buckley

Affiliations South Asian Clinical Toxicology Research Collaboration, Sri Lanka, Professorial Unit, Department of Medicine, University of New South Wales, Sydney, Australia

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

ICMJE criteria for authorship read and met: ME PE FW EJ NA FM LS AH SA KJ SJ LvM AHD NAB. Agree with the manuscript's results and conclusions: ME PE FW EJ NA FM LS AH SA KJ SJ LvM AHD MHRS NAB. Designed the experiments/the study: ME FW EJ MHRS NAB. Analyzed the data: ME PE FW FM AHD MHRS. Collected data/did experiments for the study: ME PE FW NA LS AH KJ LvM NAB. Enrolled patients: ME LS AH SA KJ SJ. Wrote the first draft of the paper: ME. Contributed to the writing of the paper: ME PE FW EJ NA FM LS SA AHD MHRS NAB. Responsible for the analyses of the PK/PD data: PE. Determination of cholinesterase data and analysis of cholinesterase, pesticide and oxime data: FW. Conducted the randomisation with the trial programmer, and performed interim analysis for the Chair of the Independent Data Monitoring Committee: EJ. Ran the logistics of this study in one of the centres and was involved in data auditing: FM. Contributed to the study at the initial stage of designing: SJ. Responsible for poison concentration data: LvM. Oversaw the two clinical centres involved in the study, examined and validated the primary data: AHD.