About the Authors

Frances Humby

Contributed equally to this work with: Frances Humby, Michele Bombardieri

Affiliation William Harvey Research Institute, Barts and the London School of Medicine, Charterhouse Square, London, United Kingdom

Michele Bombardieri

Contributed equally to this work with: Frances Humby, Michele Bombardieri

Affiliation William Harvey Research Institute, Barts and the London School of Medicine, Charterhouse Square, London, United Kingdom

Antonio Manzo

Affiliation William Harvey Research Institute, Barts and the London School of Medicine, Charterhouse Square, London, United Kingdom

Stephen Kelly

Affiliation William Harvey Research Institute, Barts and the London School of Medicine, Charterhouse Square, London, United Kingdom

Mark C Blades

Affiliation William Harvey Research Institute, Barts and the London School of Medicine, Charterhouse Square, London, United Kingdom

Bruce Kirkham

Affiliation Department of Rheumatology, Kings College London, Guy's Hospital, St Thomas Street, London, United Kingdom

Jo Spencer

Affiliation Division of Infection, Immunity and Inflammatory Diseases, Kings College London, Guy's Hospital, St Thomas Street, London, United Kingdom

Costantino Pitzalis

To whom correspondence should be addressed. E-mail: c.pitzalis@qmul.ac.uk

Affiliation William Harvey Research Institute, Barts and the London School of Medicine, Charterhouse Square, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

FH and MB conceived the study design, performed the experiments, interpreted data and wrote the manuscript. AM performed experiments, interpreted data and contributed to methodology and manuscript preparation. SK collected tissue samples. MCB performed tissue transplantation and interpreted data. BK contributed to manuscript preparation. JS contributed to methodology and critically reviewed the manuscript. CP led the team effort as well as the study design, data interpretation and manuscript preparation.