Modelling the Impact of Artemisinin Combination Therapy and Long-Acting Treatments on Malaria Transmission Intensity

Lucy C Okell; Chris J Drakeley; Teun Bousema; Christopher J. M Whitty; Azra C Ghani

doi:10.1371/journal.pmed.0050226

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Open Access

Peer-reviewed

Research Article

Modelling the Impact of Artemisinin Combination Therapy and Long-Acting Treatments on Malaria Transmission Intensity

Lucy C Okell ,

*To whom correspondence should be addressed. E-mail: Lucy.Okell@lshtm.ac.uk

Affiliation Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Chris J Drakeley,

Affiliation Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Teun Bousema,

Affiliation Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Christopher J. M Whitty,

Affiliation Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Azra C Ghani

Affiliation MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
⨯

Modelling the Impact of Artemisinin Combination Therapy and Long-Acting Treatments on Malaria Transmission Intensity

Lucy C Okell,
Chris J Drakeley,
Teun Bousema,
Christopher J. M Whitty,
Azra C Ghani

Published: November 25, 2008
https://doi.org/10.1371/journal.pmed.0050226

About the Authors

Lucy C Okell

*To whom correspondence should be addressed. E-mail: Lucy.Okell@lshtm.ac.uk

Affiliation Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

Chris J Drakeley

Affiliation Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

Teun Bousema

Affiliation Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Christopher J. M Whitty

Affiliation Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

Azra C Ghani

Affiliation MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

LCO conceived the study, carried out the analysis and drafted the paper; CJD, TB and CJMW contributed substantially to the design and interpretation and revised the manuscript critically; ACG was involved closely in all stages of the conception, design, and analysis for the study, and editing of the manuscript.

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Antimalarials
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Malaria
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Parasitic diseases
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Malarial parasites
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Prophylaxis
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Tanzania
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Artemisinin
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Drug therapy
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