About the Authors

Mark J Caulfield

Contributed equally to this work with: Mark J Caulfield, Patricia B Munroe

To whom correspondence should be addressed. E-mail: m.j.caulfield@qmul.ac.uk

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Patricia B Munroe

Contributed equally to this work with: Mark J Caulfield, Patricia B Munroe

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Deb O'Neill

Affiliation Department of Physiology, University of Alberta, Edmonton, Alberta, Canada

Kate Witkowska

Affiliation Department of Physiology, University of Alberta, Edmonton, Alberta, Canada

Fadi J Charchar

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Manuel Doblado

Affiliation Department of Obstetrics and Gynaecology, Washington University in St Louis School of Medicine, St. Louis, Missouri, United States of America

Sarah Evans

Affiliation Department of Obstetrics and Gynaecology, Washington University in St Louis School of Medicine, St. Louis, Missouri, United States of America

Susana Eyheramendy

Affiliation Department of Statistics, Pontificia Universidad Católica de Chile, Santiago, Chile

Abiodun Onipinla

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Philip Howard

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Sue Shaw-Hawkins

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Richard J Dobson

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Chris Wallace

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Stephen J Newhouse

Affiliation Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, United Kingdom

Morris Brown

Affiliation Clinical Pharmacology Unit, University of Cambridge, Addenbrookes Hospital, Cambridge, United Kingdom

John M Connell

Affiliation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom

Anna Dominiczak

Affiliation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom

Martin Farrall

Affiliation Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

G. Mark Lathrop

Affiliation Centre National de Génotypage, Evry, France

Nilesh J Samani

Affiliations Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom , Epidemiology and Public Health, University College, London, United Kingdom

Meena Kumari

Affiliation Epidemiology and Public Health, University College, London, United Kingdom

Michael Marmot

Affiliation Epidemiology and Public Health, University College, London, United Kingdom

Eric Brunner

Affiliation Epidemiology and Public Health, University College, London, United Kingdom

John Chambers

Affiliation National Heart Lung Institute and Epidemiology and Public Health, Imperial College, London, United Kingdom

Paul Elliott

Affiliation National Heart Lung Institute and Epidemiology and Public Health, Imperial College, London, United Kingdom

Jaspal Kooner

Affiliation National Heart Lung Institute and Epidemiology and Public Health, Imperial College, London, United Kingdom

Maris Laan

Affiliation Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Elin Org

Affiliation Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Gudrun Veldre

Affiliations Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia , Department of Cardiology, University of Tartu, Tartu, Estonia

Margus Viigimaa

Affiliation Centre of Cardiology, North Estonia Medical Centre, Tallinn, Estonia

Francesco P Cappuccio

Affiliation Cardiovascular Medicine and Epidemiology, Clinical Sciences Research Institute, University of Warwick Medical School, Clifford Bridge Road, Coventry, United Kingdom

Chen Ji

Affiliation Cardiovascular Medicine and Epidemiology, Clinical Sciences Research Institute, University of Warwick Medical School, Clifford Bridge Road, Coventry, United Kingdom

Roberto Iacone

Affiliation Department of Clinical and Experimental Medicine, Federico II University of Naples Medical School, Naples, Italy

Pasquale Strazzullo

Affiliation Department of Clinical and Experimental Medicine, Federico II University of Naples Medical School, Naples, Italy

Kelle H Moley

Affiliation Department of Obstetrics and Gynaecology, Washington University in St Louis School of Medicine, St. Louis, Missouri, United States of America

Chris Cheeseman

Affiliation Department of Physiology, University of Alberta, Edmonton, Alberta, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

M.J. Caulfield, P.B. Munroe, F.J. Charchar, K.H. Moley, and C. Cheeseman contributed to study design, execution, planning, analysis, and writing of the manuscript. D. O'Neill, K. Witkowska, M. Doblado, S. Evans, P. Howard, S. Newhouse, A. Onipinla, S. Shaw-Hawkins, R. Dobson, C. Wallace, M. Brown, J. Connell, A. Dominiczak, G.M. Lathrop, N.J. Samani, M. Marmot, E. Brunner, J. Chambers, P. Elliott, J. Kooner, M. Laan, E. Org, G. Veldre, and M. Viigimaa contributed to design and execution of the study. S. Eyheramendy, M. Farrall, M. Kumari, F. Cappuccio, C. Ji, R. Iacone, and P. Strazzullo contributed to design, execution, and analysis.