About the Authors

Almut Grenz

Affiliations Department of Pharmacology and Toxicology, Tübingen University Hospital, Tübingen, Germany , Mucosal Inflammation Program, Department of Anesthesiology and Perioperative Medicine, University of Colorado Health Sciences Center, Denver, Colorado, United States of America

Hartmut Osswald

Affiliation Department of Pharmacology and Toxicology, Tübingen University Hospital, Tübingen, Germany

Tobias Eckle

Affiliations Mucosal Inflammation Program, Department of Anesthesiology and Perioperative Medicine, University of Colorado Health Sciences Center, Denver, Colorado, United States of America , Department of Anesthesiology and Intensive Care Medicine, Tübingen University Hospital, Tübingen, Germany

Dan Yang

Affiliation Department of Biochemistry and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts, United States of America

Hua Zhang

Affiliation Department of Pharmacology and Toxicology, Tübingen University Hospital, Tübingen, Germany

Zung Vu Tran

Affiliation Department of Biostatistics, University of Colorado, Denver, Colorado, United States of America

Karin Klingel

Affiliation Department of Molecular Pathology, Tübingen University Hospital, Tübingen, Germany

Katya Ravid

Affiliation Department of Biochemistry and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts, United States of America

Holger K Eltzschig

To whom correspondence should be addressed. E-mail: holger.eltzschig@uchsc.edu

Affiliations Mucosal Inflammation Program, Department of Anesthesiology and Perioperative Medicine, University of Colorado Health Sciences Center, Denver, Colorado, United States of America , Department of Anesthesiology and Intensive Care Medicine, Tübingen University Hospital, Tübingen, Germany

Competing Interests

Bayer HealthCare has patented the use of the A2BAR agonist BAY 60-6583 in the treatment of different medical conditions. The authors are not associated with Bayer HealthCare and are not involved in the patent application. The authors report no competing interests.

Author Contributions

AG, HO, TE, KR, and HKE designed the experiments/the study. AG, TE, DY, HZ, KK, and KR collected data or did experiments for the study. AG, ZVT, KK, KR, and HKE analyzed the data. AG, HO, ZVT, KR, and HKE contributed to writing the paper.