About the Authors

Hans Bisgaard

To whom correspondence should be addressed. E-mail: bisgaard@copsac.com

Affiliation Copenhagen Prospective Studies on Asthma in Childhood, Danish Paediatric Asthma Centre, Copenhagen, University Hospital Gentofte, Copenhagen, Denmark

Angela Simpson

Affiliation School of Translational Medicine, University of Manchester, University Hospital of South Manchester National Health Service Foundation Trust, Manchester, United Kingdom

Colin N.A Palmer

Affiliation Population Pharmacogenetics Group, Biomedical Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom

Klaus Bønnelykke

Affiliation Copenhagen Prospective Studies on Asthma in Childhood, Danish Paediatric Asthma Centre, Copenhagen, University Hospital Gentofte, Copenhagen, Denmark

Irwin Mclean

Affiliation Population Pharmacogenetics Group, Biomedical Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom

Somnath Mukhopadhyay

Affiliation Royal Alexandra Children's Hospital, Brighton and Sussex Medical School, Brighton, United Kingdom

Christian B Pipper

Affiliation Copenhagen Prospective Studies on Asthma in Childhood, Danish Paediatric Asthma Centre, Copenhagen, University Hospital Gentofte, Copenhagen, Denmark

Liselotte B Halkjaer

Affiliation Copenhagen Prospective Studies on Asthma in Childhood, Danish Paediatric Asthma Centre, Copenhagen, University Hospital Gentofte, Copenhagen, Denmark

Brian Lipworth

Affiliation Asthma and Allergy Research Group, Division of Medicine and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Scotland, United Kingdom

Jenny Hankinson

Affiliation School of Translational Medicine, University of Manchester, University Hospital of South Manchester National Health Service Foundation Trust, Manchester, United Kingdom

Ashley Woodcock

Affiliation School of Translational Medicine, University of Manchester, University Hospital of South Manchester National Health Service Foundation Trust, Manchester, United Kingdom

Adnan Custovic

Affiliation School of Translational Medicine, University of Manchester, University Hospital of South Manchester National Health Service Foundation Trust, Manchester, United Kingdom

Competing Interests

HB has been a consultant to, paid lecturer for, and holds sponsored grants from AstraZeneca, GSK, Merck, MedImmune, NeoLab, and Pfizer. He does not hold stock or options in any pharmaceutical company in the respiratory field. IM has filed two patents relating to genetic testing and therapy development aimed at the filaggrin gene. AC receives grant and research support from GlaxoSmithKline and is a consultant for GlaxoSmithKline and UCB Pharma, ALK; and at the speaker's bureau of Astra-Zeneca, GlaxoSmithKline, and UCB Pharma, ALK.

Author Contributions

HB, CNAP, and AC conceived and designed the study and obtained funding. KB and LBH collected and assembled the data. HB and AC analysed and interpreted the data. CBP provided statistical expertise. HB drafted the article. AS, CNAP, KB, IM, SM, CBP, LBH, BL, JH, AW, and AC contributed to the critical revision of the article for important intellectual content. HB, AS, CNAP, KB, IM, SM, CBP, LBH, BL, JH, AW, and AC contributed to the final approval of the article and provision of study materials or patients.