About the Authors

Mirjam E Meltzer

Affiliations Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, The Netherlands , Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands

Ton Lisman

Affiliations Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, The Netherlands , Surgical Research Laboratory, Department of Surgery, University Medical Centre Groningen, University of Groningen, Utrecht, The Netherlands

Carine J. M Doggen

Affiliation Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands

Philip G de Groot

Affiliation Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, The Netherlands

Frits R Rosendaal

To whom correspondence should be addressed. E-mail: f.r.rosendaal@lumc.nl

Affiliations Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands , Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands , Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MEM, TL, CJMD, and FRR designed and coordinated the study. MEM analysed the data. MEM, CJMD, TL, PGdG, and FRR contributed to writing the paper.